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Chemical Name: 3-(N-Morpholino)propanesulfonic acid
Common Name: MOPS
CAS Number: 1132-61-2
Product Codes: M1254, M8889, Other commercial references
Recommended Use: Laboratory buffer for biological research
Manufacturer: Detailed company and emergency contact information provided by supplier
Synonyms: 4-Morpholinepropanesulfonic acid, MOPS buffer
Classification: Eye irritation (Category 2A), non-volatile solid may cause mild irritation to eyes and skin
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, may cause respiratory irritation, prolonged contact can trigger mild skin irritation
Pictograms: Exclamation Mark (GHS07)
Precautionary Statements: Wear protective eyewear and gloves, avoid breathing dust, use only in well-ventilated spaces
Other Hazards: Fine powder form may pose a dust explosion hazard in high concentrations
Chemical Identity: 3-(N-Morpholino)propanesulfonic acid
Concentration: ≥98% by weight
Molecular Formula: C7H15NO4S
Molecular Weight: 209.27 g/mol
Impurities: Usually negligible in research grade material
Inhalation: Move to fresh air, seek medical attention if breathing becomes difficult or symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water, seek medical guidance if irritation or redness develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, obtain medical help if discomfort continues
Ingestion: Rinse mouth thoroughly, do not induce vomiting, call a poison center or physician, provide medical records and product details
Most Important Symptoms: Eye discomfort, mild skin irritation, throat irritation if inhaled
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Strong water jets
Special Hazards: Burning may emit toxic fumes (sulfur oxides, nitrogen oxides, carbon monoxide)
Advice for Firefighters: Wear self-contained breathing apparatus, operate from upwind position, avoid smoke inhalation
Additional Information: Use water spray to cool fire-exposed containers
Personal Precautions: Avoid dust formation, ventilate area, wear gloves, goggles, and lab coat
Environmental Precautions: Keep out of drains, sewers, and waterways
Methods for Containment: Sweep up gently, avoid creating airborne dust
Cleanup Methods: Collect spill with shovel or vacuum in accordance with local regulations, place in labelled waste container
Reference to Other Sections: Refer to exposure controls and disposal information below
Precautions for Safe Handling: Use in well-ventilated area, minimize dust generation, avoid contact with skin and eyes
Hygienic Practices: Wash hands thoroughly after use, do not eat or drink near material
Safe Storage Conditions: Keep container tightly sealed, store in cool, dry place away from incompatible materials (strong oxidizing agents)
Incompatible Materials: Strong oxidizers, strong acids
General Guidance: Store separate from food and animal feed
Exposure Limits: No established OSHA, ACGIH, or NIOSH limits for MOPS
Engineering Controls: Laboratory fume hood or local exhaust, safety shower and eyewash station nearby
Personal Protective Equipment: Protective gloves (nitrile or neoprene), safety goggles, lab coat
Respiratory Protection: Dust mask if airborne concentrations become excessive
Environmental Controls: Prevent release to environment, use secondary containment when handling larger volumes
Physical State: Solid powder or crystalline
Color: White to off-white
Odor: None
Odor Threshold: Not applicable
pH (1% Solution): Approximately 3.0 (acidic)
Melting Point: 289–291 °C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Flammability: Low (not easily ignited)
Explosive Properties: Fine dust may pose explosion risk in confined areas
Vapor Pressure: Negligible at room temperature
Relative Density: ~1.4 g/cm³
Solubility in Water: 40–50 g/L (at 25 °C)
Partition Coefficient: Not determined
Auto-Ignition Temperature: Not self-igniting
Decomposition Products: Sulfur oxides, nitrogen oxides, carbon oxides
Chemical Stability: Stable under normal laboratory conditions
Thermal Decomposition: Decomposes on heating above 289 °C
Reactivity: No hazardous reactions with water, acids, or bases under typical use
Conditions to Avoid: Excessive heat, moisture, sources of ignition, incompatible chemicals
Materials to Avoid: Strong oxidizers and strong acids
Hazardous Decomposition Products: Produces sulfur oxides and nitrogen oxides if combusted
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low toxicity, LD50 in animals exceeds 5000 mg/kg (oral, rat)
Irritation: May cause mild skin and significant eye irritation upon prolonged or repeated exposure
Sensitization: Not considered a skin sensitizer
Chronic Effects: Data not sufficient for long-term effects
Carcinogenicity: Not listed by NTP, IARC, or OSHA as carcinogenic
Mutagenicity: No evidence for mutagenic effects
Reproductive Toxicity: Not known to impact fertility or birth outcomes
Ecotoxicity: Expected to have low acute toxicity to aquatic organisms
Persistence and Degradability: Slowly biodegradable under environmental conditions
Bioaccumulative Potential: Low, based on water solubility and molecular structure
Mobility in Soil: Likely to partition into water phase due to solubility
Other Adverse Effects: Not identified as hazardous to the environment at working concentrations but limit release to surface water
Waste Treatment Methods: Mix with compatible absorbent and dispose as laboratory chemical waste
Disposal Regulations: Follow local, regional, and federal rules for non-hazardous organic waste
Container Disposal: Triple-rinse, deface label, dispose in accordance with chemical waste regulations
Precautions: Avoid uncontrolled release to drains or the environment
Precautionary Disposal: Use appropriate PPE, document all significant disposals
UN Number: Not regulated for transport
UN Proper Shipping Name: Not assigned
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not required
Marine Pollutant: No
Special Precautions: Protect from moisture and physical damage during transportation
Transport Documentation: Ship as per routine laboratory chemicals, avoid mixing with oxidizing materials in transit
TSCA: Listed
DSL/NDSL (Canada): Listed
EU REACH: Exempted under registration requirements for research chemicals
SARA Title III (Sections 302, 311/312, 313): Not subject to hazardous reporting
California Proposition 65: Not listed
Other Regulatory Status: Complies with GHS globally harmonized system for labeling and classification
Workplace Labeling: Required in laboratory and industrial settings according to local regulations
