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Material Safety Data Sheet (MSDS): 3-Indolebutyric Acid

Identification

Product Name: 3-Indolebutyric Acid
Synonyms: IBA, 4-(3-Indolyl)butyric acid
Chemical Formula: C12H13NO2
Molecular Weight: 187.24
CAS Number: 133-32-4
Recommended Use: Plant growth regulator, rooting hormone
Supplier: Contact local distributor or manufacturer for specific details
Contact Information: Supplier phone and emergency contact should be included on the actual document

Hazard Identification

Classification: Not classified as hazardous according to GHS standards when used as directed
Potential Hazards: May cause skin, eye, and respiratory irritation on contact or inhalation
Symbol: No universally required pictogram, but caution advised
Signal Word: Warning
Hazard Statement: Can irritate mucous membranes, prolonged contact may provoke mild skin or eye irritation
Precautionary Measures: Use personal protective equipment, avoid dust creation, do not ingest
Long-term Effects: No known chronic effects with typical use in agriculture, but prudent care lowers risk

Composition / Information on Ingredients

Chemical Name: 3-Indolebutyric Acid
Concentration: Typically 99% pure in laboratory and technical grade
Impurities: Trace levels of related indole derivatives, less than 1%
Other Ingredients: Not intentionally added in pure formulations
CAS Registry Number: 133-32-4

First Aid Measures

Inhalation: Move to fresh air, seek medical attention if symptoms develop or persist
Skin Contact: Wash affected area thoroughly with soap and plenty of water, remove contaminated clothing
Eye Contact: Rinse eyes gently with plenty of water for at least 15 minutes, lifting eyelids to ensure thorough cleansing
Ingestion: Rinse mouth with water, never attempt to induce vomiting unless instructed by a medical professional, seek medical advice if large amounts are swallowed
Symptoms of Exposure: Redness, irritation, coughing, headache in excessive dust exposure scenarios
Special Notes for Physicians: Treat symptomatically, monitor respiratory and skin status

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Media: Avoid using direct water jet; may spread material
Specific Hazards: Slightly combustible; may emit nitrogen oxides, carbon monoxide, and carbon dioxide on burning
Protective Equipment: Firefighters should wear self-contained breathing apparatus and chemical-resistant gear
Firefighting Techniques: Approach from upwind, prevent run-off from entering drains, isolate danger area
Combustion Products: Toxic fumes such as COx and NOx possible

Accidental Release Measures

Spill Response: Avoid dust formation, ventilate area, sweep up and place in a suitable chemical waste container
Environmental Precautions: Prevent entry into drains or natural waterways
Personal Precautions: Wear gloves, goggles, dust mask or respirator as needed
Cleanup Methods: Sweep or vacuum, use damp cloths for final cleanup on hard surfaces
Disposal: Place residues in labeled, sealed containers with hazardous waste collection procedures in mind

Handling and Storage

Handling Procedures: Handle in a well-ventilated area, avoid breathing dust and contact with skin, eyes, or clothing
Safe Storage: Keep container tightly closed and in a cool, dry, well-ventilated place away from incompatible substances like strong oxidizers, acids, or alkalis
Special Precautions: Avoid open flames, spark sources, and static discharge
Transfer Requirements: Use non-sparking tools and grounding or bonding where appropriate
Incompatibility: Strong oxidizing agents and bases

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits set for 3-Indolebutyric Acid
Engineering Controls: Mechanical exhaust, local ventilation recommended whenever dust can form
Personal Protective Equipment: Nitrile or neoprene gloves, chemical goggles or face shield, dust mask or respirator for powder handling, laboratory coat or protective clothing
Hygiene Practices: Wash hands thoroughly after handling, remove and wash contaminated clothing before reuse, avoid eating, drinking, or smoking during use
Workplace Controls: Maintain eyewash stations and safety showers in work areas

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Slight or no distinct odor
pH: 4–5 (1% solution in water)
Melting Point: 123–125°C
Boiling Point: Decomposes before boiling
Solubility: Poor solubility in water; soluble in ethanol, DMSO, and acetone
Vapor Pressure: Not applicable due to low volatility
Relative Density: Approximately 1.25 g/cm³ (at 20°C)
Flash Point: Not available; considered minimal fire risk at ambient temperatures
Partition Coefficient (log Kow): Estimated 2.7–3.1
Other Data: Stable under recommended storage, may discolor with light or exposure to air

Stability and Reactivity

Chemical Stability: Stable at room temperature and under recommended storage conditions
Thermal Decomposition: May break down to toxic gases such as carbon monoxide and nitrogen oxides at high temperatures
Reactivity: No dangerous reactions known under normal use
Incompatibility: Avoid strong oxidizers, strong acids, and strong bases to prevent hazardous reactions
Hazardous Polymerization: Not known to occur
Conditions to Avoid: Prolonged exposure to heat, open flame, moisture, direct sunlight

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity (LD50): Oral (rat): 1000–5000 mg/kg; relatively low toxicity
Skin Corrosion/Irritation: Minor, non-corrosive, possible mild irritation
Eye Damage/Irritation: May cause eye irritation with direct contact
Respiratory Sensitization: Rare; dust may provoke mild respiratory symptoms
Chronic Effects: No published data suggesting carcinogenicity, mutagenicity, or reproductive toxicology in humans
Other Health Effects: No known systemic toxicity at levels typically encountered in agricultural or research applications

Ecological Information

Aquatic Toxicity: Not classified as toxic to aquatic life at environmental dosages, but avoid release to significant bodies of water
Mobility in Soil: Moderately mobile; may leach in sandy soil, less so in clay
Persistence and Degradability: Degrades over days to weeks in soil under natural conditions, especially with microbial action
Bioaccumulative Potential: Low; some studies suggest limited accumulation in aquatic organisms
Other Harmful Effects: Large-scale accidental releases may harm sensitive algae and invertebrates in receiving waters

Disposal Considerations

Disposal Methods: Collect and place waste in properly labeled and sealed containers
Hazardous Waste Code: Consult national/regional regulations; not classified as hazardous waste in many jurisdictions
Safe Handling: Minimize dust, avoid spills and runoff
Incineration: Permitted under controlled conditions if allowed by local regulations
Disposal of Packaging: Rinse thoroughly, dispose or recycle according to local, regional, or national requirements

Transport Information

UN Number: Not regulated for ground, air, or sea transportation
Proper Shipping Name: Not classified as a dangerous good
Transport Hazard Class: None
Packing Group: None
Special Precautions: Use sealed, properly labeled packaging; protect from excessive heat and moisture during transit
Transport Labeling: General chemical goods labeling applies

Regulatory Information

International Inventories: Present on TSCA, EINECS, AICS, DSL, and comparable chemical inventories
Regulatory Status: Not subject to special registration under REACH or OSHA for most uses
Workplace Safety: General chemical hygiene plans cover the required handling precautions
SARA Title III: Not listed
California Proposition 65: Not listed
Other: Always consult the latest local, national, and international regulations to verify compliance