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Chemical Name: 3-Aminoquinoline
Chemical Formula: C9H8N2
Synonyms: none often found for this structure
Physical Appearance: solid, typically off-white or light yellow
Recommended Use: laboratory research, intermediate in pharmaceutical synthesis
Hazards Classification: irritant to eyes, skin, and respiratory system
Primary Hazards: exposure can bring eye and skin redness, respiratory discomfort, coughing after inhalation of dust
GHS Pictograms: exclamation mark for acute toxicity and skin/eye irritancy
Signal Word: Warning
Hazard Statements: causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: avoid breathing dust, use only with adequate ventilation, wash thoroughly after handling, wear suitable protective equipment
Chemical Identity: 3-Aminoquinoline
Purity: greater than 98% by weight is standard in research-grade material
Impurities: small presence of related quinolines in some samples, typically less than 2%
CAS Number: 612-52-2
Inhalation: remove individual to fresh air, support breathing as needed, consult a physician if symptoms persist
Skin Contact: remove contaminated clothing, wash area with soap and water, seek medical guidance if irritation continues
Eye Contact: flush gently with plenty of clean water for at least 15 minutes, keep eyelids apart, medical attention needed if discomfort lingers
Ingestion: rinse mouth, do not induce vomiting, seek immediate medical care
Notes for Physician: treat symptomatically, maintain airway and respiration
Suitable Extinguishing Agents: foam, dry powder, carbon dioxide, sand
Specific Hazards: emits toxic nitrogen oxides and carbon oxides when heated strongly or incinerated
Protective Actions: firefighters wear self-contained breathing apparatus and full protective coat
Additional Notes: avoid allowing contaminated water runoff into drains or natural bodies
Personal Precautions: avoid inhalation and skin contact, ventilate area, use personal protective equipment
Spill Procedures: sweep up using non-sparking tools, collect material into sealed containers for disposal
Environmental Measures: prevent release to soil, drains, or waterways
Clean-up: wash area with sufficient water after full material recovery
Handling Practices: work in well-ventilated space, handle away from open flames and spills, avoid mechanical shock and static discharge
Storage Conditions: store in tightly closed containers, keep in cool, dry, well-ventilated spot, limit exposure to light and air
Incompatibilities: oxidizing agents and strong acids react with 3-Aminoquinoline
Engineering Controls: use fume hood or local exhaust
Personal Protective Equipment: chemical-resistant gloves, safety goggles, protective lab coat
Respiratory Protection: wear approved dust mask or respirator for large-scale handling
Hygiene Practices: wash hands thoroughly after use, keep contaminated clothing separate
Appearance: pale yellow to white crystalline powder
Odor: slight, sometimes musty
Melting Point: measured around 100–120°C
Boiling Point: not readily available, substance may decompose before boiling
Solubility: limited solubility in water, more soluble in organic solvents like ethanol and chloroform
Density: about 1.2–1.3 g/cm³, varies depending on sample and temperature
Chemical Stability: stable under normal experimental and storage conditions
Reactivity: reacts with strong oxidizers and acids, forming potentially hazardous by-products
Conditions to Avoid: moisture, excessive heat, light
Hazardous Decomposition Products: nitrogen oxides, carbon monoxide, carbon dioxide
Routes of Exposure: inhalation, skin and eye contact, ingestion
Acute Effects: irritation to eyes, skin, and upper respiratory tract, can cause nausea or headache if ingested
Chronic Effects: evidence from quinoline derivatives suggests potential for liver and kidney effects in long exposures, though data on 3-Aminoquinoline is limited
Carcinogenicity: limited evidence, no official classification by IARC or related bodies
Sensitization: not classified as a sensitizer
Aquatic Toxicity: expected to be harmful to aquatic life at moderate levels, limited biodegradability
Persistence and Degradability: not readily biodegradable, can persist in soil and waterways
Bioaccumulation Potential: estimated to be low. Specific studies are scarce
Mobility in Soil: may migrate if released in bulk
Disposal Methods: incineration in licensed chemical waste facility, avoid direct release to natural waters
Contaminated Packaging: treat as hazardous waste, clean containers thoroughly before recycling or disposal
UN Number: not assigned
Transport Hazard Class: not regulated for most ground shipment as dangerous goods
Precautions: transport in sealed, secure containers, keep away from incompatible materials
Special Considerations: avoid extreme temperatures during shipment
Labeling Requirements: proper hazard pictograms, warning labels, and risk statements by workplace safety guidelines
Workplace Classification: regulated as a hazardous substance in laboratories, subject to typical chemical safety laws
Environmental Regulation: control accidental releases, report significant spills under local guidelines
Other Notations: safety training recommended for laboratory personnel
