© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 3,3'-Diaminobenzidine Tetrahydrochloride
Synonyms: DAB, Diaminobenzidine, DAB·4HCl
Chemical Formula: C12H14Cl4N4
CAS Number: 7411-49-6
Recommended Use: Laboratory reagent, Histological stain
Manufacturer: Refer to product label
Emergency Contact: Refer to supplier’s instructions
Classification: Harmful if swallowed, Skin and eye irritant, Suspected carcinogen
GHS Label Elements: Pictogram: Health hazard, Exclamation mark
Signal Word: Warning
Hazard Statements: H302: Harmful if swallowed, H315: Causes skin irritation, H319: Causes serious eye irritation, H351: Suspected of causing cancer
Precautionary Statements: Do not breathe dust, wear protective gloves and safety glasses, wash skin thoroughly after handling, avoid contact with eyes and skin
Potential Health Effects: May cause abdominal discomfort, nausea, skin rashes, eye redness, respiratory symptoms, risk of long-term organ damage
Chemical Name: 3,3'-Diaminobenzidine Tetrahydrochloride
Concentration: ≥98%
CAS Number: 7411-49-6
Impurities: Hydrochloride residues <2%
Other Ingredients: None detected under normal manufacturing conditions
General Advice: Remove contaminated clothing, seek fresh air
Inhalation: Move to open air, get medical help for difficulty breathing
Skin Contact: Wash thoroughly with soap and water, remove any residue, seek medical attention for persistent irritation
Eye Contact: Rinse eyes with water for at least 15 minutes, lift eyelids occasionally, get prompt medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical consultation
Most Important Symptoms: Burning, coughing, abdominal pain, rash, blurred vision
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam
Hazards: Emits toxic fumes under fire conditions (nitrogen oxides, hydrochloric acid vapors), risk of explosion if heated above decomposition temperature
Firefighting Instructions: Wear self-contained breathing apparatus, full protective gear, avoid inhaling combustion vapors
Special Risks: Avoid water streams that may spread the material, evacuate area if fire involves large quantity, use only trained personnel for containment
Personal Precautions: Evacuate unnecessary personnel, ventilate area, wear gloves, eye protection, dust mask
Environmental Precautions: Prevent powder from entering drains, sewers, waterways
Clean-up Methods: Scoop up into containers for disposal, avoid generating dust, wipe residues with wet absorbent, launder contaminated clothing
Spill Handling: Prevent spread, mark contaminated area, call hazardous materials experts for substantial quantities
Handling Precautions: Keep container sealed, avoid breathing dust, use only with adequate ventilation, clean spills promptly, store away from incompatible materials
Safe Storage Conditions: Store cool and dry, out of direct sunlight, away from oxidizers and bases, in properly labeled containers
Incompatible Materials: Strong oxidizing agents, strong bases, metals
Safe Transfer Advice: Use designated handling tools, avoid manual transfer, maintain rigorous hygiene practices
Occupational Exposure Limits: Not established by OSHA, ACGIH, or NIOSH
Engineering Controls: Use fume hoods, local exhaust ventilation, keep airborne levels low
Respiratory Protection: Use properly fitted NIOSH-approved respirator for fine particulates
Hand Protection: Chemical-resistant gloves (nitrile or neoprene recommended)
Eye Protection: Chemical splash goggles
Skin/Body Protection: Lab coat, closed footwear, long sleeves
Hygiene Measures: Wash before breaks and after handling, do not eat or drink near area
Appearance: Light brown to beige crystalline powder
Odor: Odorless
Molecular Weight: 377.08 g/mol
Melting Point: 257°C
Boiling Point: Not available
Solubility: Soluble in water
pH (1% in water): 2–4
Vapor Pressure: Negligible
Flash Point: Not applicable (non-flammable solid)
Partition Coefficient (octanol/water): Not determined
Chemical Stability: Stable under recommended storage conditions
Possible Hazardous Reactions: Can react with oxidizers and strong bases
Decomposition Products: Toxic gases, including nitrogen oxides, hydrogen chloride
Conditions to Avoid: Avoid excess heat, moisture, direct sunlight, open flames
Polymerization: Will not occur under normal conditions
Acute Toxicity: Oral LD50 (rat) not available, harmful in moderate doses
Skin Corrosion/Irritation: Causes irritation on contact
Serious Eye Damage/Irritation: Highly irritating to eyes
Respiratory Effects: May cause coughing, shortness of breath, nasal irritation
Carcinogenicity: Classified by IARC as Group 2B (possibly carcinogenic to humans); experimental data show positive results in animal models
Mutagenicity: Evidence of mutagenic effects in bacterial and mammalian cell assays
Other Effects: May aggravate pre-existing skin or respiratory conditions
Ecotoxicity: Toxic to aquatic life with long lasting effects
Persistence and Degradability: Not readily biodegradable, remains in environment
Bioaccumulation Potential: No data, potential to bioaccumulate based on structure
Mobility in Soil: Likely to adsorb to soils and particles
Other Adverse Effects: Avoid contamination of water bodies, risk for laboratory wastewater systems
Waste Handling: Dispose of in accordance with local, regional, and national regulations
Container Disposal: Rinse thoroughly, destroy or return to supplier
Methods: Incinerate in chemical incinerator equipped with afterburner and scrubber
Recommendation: Do not dump in garbage, avoid wastewater release, use authorized waste disposal contractors
UN Number: Not regulated by ADR/RID/IMDG/IATA for most laboratory quantities
Proper Shipping Name: Laboratory chemicals, n.o.s.
Hazard Class: Non-regulated for sample volumes, review site-specific rules for large shipments
Packing Group: Not assigned
Special Precautions: Transport in sealed, labeled containers within secondary packaging to prevent release or contact
TSCA: Listed
SARA 313: Not listed
California Proposition 65: May contain chemicals known to the State of California to cause cancer
EU Regulation: Subject to REACH registration, classified as hazardous
WHMIS Classification (Canada): Class D2A – Very toxic material causing other toxic effects
Other Regulations: Product intended for use by qualified personnel trained in proper laboratory safety and hazardous chemical handling procedures
