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Product Name: 2-Pivaloyl-2,3-Dihydro-1,3-Indandione
Synonyms: Pivaloylindandione; 2,3-Dihydro-1,3-Indandione, 2-pivaloyl derivative
CAS Number: 65157-97-3
Recommended Use: Laboratory chemical, intermediate for synthesis
Supplier Details: Chemical manufacturer or distributor, address, emergency phone number and standard phone number for inquiries
Emergency Phone: Continuous access number typically provided by local, regional, or international chemical safety authority
Classification: Flammable solid, Harmful if inhaled or swallowed, Causes eye irritation, Causes skin irritation
Signal Word: Warning
Hazard Statements: May cause respiratory tract and skin irritation; Harmful if ingested or inhaled; May cause eye damage
Pictograms: Exclamation mark, health hazard, flame
Precautionary Statements: Keep away from ignition sources; avoid breathing dust and vapors; use personal protective equipment as required; wash hands and skin thoroughly after handling; if in eyes, rinse cautiously with water
Other Hazards: Dust explosion possible if dispersed in air; may form hazardous decomposition products under fire conditions
Chemical Name: 2-Pivaloyl-2,3-Dihydro-1,3-Indandione
CAS Number: 65157-97-3
Percentage: ≥97% (by weight)
Impurities/Other Components: Remaining balance consists of trace contaminants and byproducts from manufacturing
Molecular Formula: C13H14O3
Molecular Weight: 218.25 g/mol
Inhalation: Move person to fresh air; keep at rest; seek medical attention if breathing becomes difficult or symptoms persist
Skin Contact: Remove contaminated clothing; immediately wash affected skin thoroughly with soap and water; seek medical advice if irritation continues
Eye Contact: Flush eyes gently with large volumes of water for at least 15 minutes while holding eyelids apart; remove contact lenses if present and easy to do; prompt medical attention important
Ingestion: Rinse mouth with water; do not induce vomiting; never give anything by mouth to an unconscious person; obtain immediate medical care
Symptoms and Effects: Irritation to eyes, skin, or respiratory tract; headache, dizziness, nausea possible from overexposure
Indications for Medical Attention: Difficulty breathing, persistent eye pain, severe allergic reaction, or prolonged symptoms
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: Direct jets of water may disperse material or spread fire
Specific Hazards Arising from Chemical: Material may emit toxic fumes such as carbon monoxide, carbon dioxide, and organic acid vapors on combustion
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Firefighting Instructions: Stay upwind; prevent run-off from entering drains; use water spray to cool containers exposed to fire
Hazards to Environment: Effluent might contaminate water sources with persistent organic residues
Personal Precautions: Keep unprotected personnel away; ensure adequate ventilation; avoid inhalation of dust or fumes; use proper personal protective equipment
Environmental Precautions: Prevent further leakage or release if safe to do so; do not allow product to enter drains, sewers, or watercourses; inform authorities if significant spillage occurs
Methods for Clean-Up: Carefully collect and place spilled material in a suitable, labeled waste container for disposal; sweep up or use vacuum with HEPA filter; wash spill site after material pick-up is complete
Reference to Other Sections: Refer to exposure controls, disposal consideration, and fire-fighting sections for further management guidance during a release
Precautions for Safe Handling: Avoid breathing dust, vapors, or fumes; minimize dust generation; wear suitable protective clothing, gloves, and eye/face protection; wash hands after use; avoid eating, drinking, or smoking during handling
Storage Requirements: Store in tightly closed containers in a dry, cool, well-ventilated area; keep away from heat sources, sparks, and open flames; separate from oxidizing agents and acids
Incompatible Materials: Strong oxidizers, acids, and bases may react violently; avoid contact with sources of ignition
Container Requirements: Use corrosion-resistant or lined containers; ensure proper labeling; secondary containment recommended in storage areas
Occupational Exposure Limits: No official workplace exposure limit set; treat as hazardous dust/chemical
Engineering Controls: Use local exhaust or general ventilation to maintain airborne levels below safe limits; safety shower and eyewash available in immediate vicinity
Respiratory Protection: Suitable respirator if exposure risk from dust or fumes, or if safe levels cannot be maintained
Eye/Face Protection: Chemical safety goggles or face shield; avoid contact lenses in laboratory settings
Skin Protection: Impervious gloves, apron, and lab coat recommended for direct handling
Hygiene Measures: Wash hands and exposed skin before breaks and after handling; remove contaminated clothing and wash before reuse
Appearance: Crystalline solid, off-white or pale yellow
Odor: Mild, characteristic organic
Odor Threshold: Not available
pH: Not applicable (insoluble in water)
Melting Point/Freezing Point: 120-124°C
Boiling Point: Decomposes before boiling
Flash Point: Estimated above 100°C
Evaporation Rate: Not measurable at room temperature
Flammability: Flammable solid
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not applicable
Solubility: Slightly soluble in water, soluble in acetone, ethanol, and other organic solvents
Partition Coefficient (log Kow): Not established; expected moderately lipophilic
Auto-ignition Temperature: No data
Decomposition Temperature: Decomposes releasing toxic fumes above melting point
Viscosity: Not applicable (solid form)
Reactivity: Stable under normal storage and handling conditions
Chemical Stability: Stable in sealed containers kept away from light, heat, and strong oxidizers
Possibility of Hazardous Reactions: May react exothermically with strong acids, bases, or oxidants; may form explosive dust-air mixtures
Incompatible Materials: Oxidizing agents, acids, alkalis
Hazardous Decomposition Products: Carbon oxides, organic vapors, pivalic acid byproducts on heating or combustion
Conditions to Avoid: Heat, open flame, sources of ignition, incompatible substances, static discharge, prolonged exposure to air/moisture
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Data scarce, estimated moderate oral and inhalation toxicity based on similar indandione compounds
Skin Corrosion/Irritation: May cause localized irritation or dermatitis
Serious Eye Damage/Irritation: Known eye irritant; may cause watering, redness, pain
Respiratory or Skin Sensitization: No studies available; expected potential for mild sensitization
Chronic Effects: No long-term data; possible liver/kidney effects in animal models of structural relatives
Carcinogenicity: Not classified by IARC, NTP, or OSHA; insufficient human data
Mutagenicity/Reproductive Toxicity: No specific tests completed; treat as potentially mutagenic based on class structure
Symptoms of Overexposure: Headache, dizziness, fatigue, skin eruptions, coughing, nausea
Ecotoxicity: Moderate aquatic toxicity expected based on persistence and low solubility; data unavailable for individual aquatic organisms
Persistence and Degradability: Expected to persist under normal environmental conditions; slow biodegradation
Bioaccumulation Potential: Possible accumulation in aquatic life forms due to moderate log Kow
Mobility in Soil: Low mobility predicted; binds to organic matter
Other Adverse Effects: Precaution advised against release to waterways; long-term effects unknown
Disposal Methods: Dispose of in accordance with federal, state, and local environmental control regulations; incineration preferred for large amounts
Packaging Disposal: Triple rinse containers before recycling or discarding; puncture and dispose to prevent reuse
Special Precautions: Avoid dust generation and release to environment; handle residue as hazardous chemical waste
UN Number: 2811 (Toxic Solid, Organic, n.o.s., if required by specific country or region)
Shipping Name: Toxic solid, organic, n.o.s. (contains 2-Pivaloyl-2,3-Dihydro-1,3-Indandione)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Not specifically identified; treat as potentially hazardous, avoid aquatic release
Special Transport Precautions: Protect packages from physical damage; ensure upright, secure containers; drivers and handlers should have completed safety training related to transport of hazardous chemicals
USA: Not listed under TSCA; SARA Title III Sec 313 reportable quantity not established; OSHA hazardous chemical
Europe: Not on ECHA SVHC list; labeling under CLP Regulation (EC) No. 1272/2008 required
Other Regulatory Data: Not classified as controlled drug or narcotic, though local restrictions may apply; chemical waste generator status impacts storage and disposal requirements
Inventory Listings: Check national chemical inventories for inclusion and compliance prior to distribution or use
Label Requirements: Appropriate pictograms, signal word, and hazard statements per GHS/CLP standards; provide SDS with all initial shipments and upon request
Workplace Control: Safety training for all laboratory or handling staff; maintain proper records of use, storage, and incidents for regulatory compliance and emergency response planning
