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Product Name: 2-Nitroiodobenzene
Chemical Formula: C6H4INO2
Synonyms: o-Iodonitrobenzene, ortho-Nitroiodobenzene
CAS Number: 583-76-0
Molecular Weight: 249.01 g/mol
Recommended Use: Laboratory chemical, chemical synthesis intermediate
Supplier: Chemical distributors and specialty suppliers
Contact Information: Refer to supplier or manufacturer
Emergency Contact: Local poison control center or national chemical emergency hotline
GHS Classification: Acute toxicity (oral, inhalation), Eye irritation, Specific target organ toxicity - single exposure
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes serious eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or vapor, wash hands thoroughly after handling, wear eye and face protection, do not eat or drink while using
Potential Health Effects: Irritation to eyes, skin, and respiratory tract, headache, dizziness, nausea if inhaled or ingested
Environmental Impact: Toxic to aquatic organisms, long lasting effects in water systems
Chemical Name: 2-Nitroiodobenzene
Concentration: >98% (technical grade)
Impurities: May contain trace amounts of related iodinated or nitrobenzene impurities (<2%)
CAS Number: 583-76-0
EC Number: 209-542-3
Molecular Structure: Benzene ring substituted by a nitro group (NO2) at position 2 and an iodine at position 1
Inhalation: Move to fresh air, keep at rest, seek medical advice if symptoms appear such as cough, sore throat, or breathing difficulty
Skin Contact: Remove contaminated clothing, rinse skin with water for several minutes, get medical attention if irritation develops
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, remove contact lenses, consult medical help if pain or redness stays
Ingestion: Rinse mouth, do not induce vomiting, seek urgent medical advice, note substance can be toxic if ingested
Note to Physician: Treat symptomatically, monitor respiratory and cardiovascular function, consider gastric lavage in severe cases
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam
Not Suitable: Direct water jet
Special Hazards: May emit toxic fumes including nitrogen oxides, hydrogen iodide, and iodine upon burning
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective gear
Additional Advice: Cool containers with water spray from a safe distance to prevent pressure build-up, evacuate area if fumes are released, avoid inhalation of smoke
Personal Precautions: Use chemical splash goggles, gloves, and laboratory coat, avoid breathing dust, ventilate area
Environmental Precautions: Prevent entry into sewers, soil, or waterways, alert local authorities in case of significant spillage
Cleanup Methods: Absorb with inert material such as sand or vermiculite, collect spills in labeled containers for disposal, clean area with water and detergent, handle as hazardous waste
Decontamination: Use appropriate personal protective equipment, avoid creating dust, wash surface thoroughly after cleanup
Handling: Avoid direct contact with skin and eyes, work in a fume hood or well-ventilated area, minimize dust generation, keep container tightly closed
Storage Conditions: Store in original, sealed containers away from light, moisture, and incompatible substances such as strong reducing agents or organic materials
Temperature Requirements: Keep at room temperature away from heat sources
Shelf Life: Stable for at least two years under recommended storage conditions
Incompatible Materials: Strong oxidizers, strong bases, strong acids, alkali metals, reducing agents
Engineering Controls: Use exhaust ventilation such as fume hoods, keep laboratory air clean
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), safety goggles, lab coat, long pants, closed-toe shoes
Respiratory Protection: Use dust mask or respirator if ventilation is inadequate or in case of high airborne concentrations
Exposure Limits: No established occupational exposure limits specific to this compound
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink in work area, remove contaminated clothing before leaving the lab
Appearance: Pale yellow to light brown crystalline powder
Odor: Slightly aromatic
Odor Threshold: Not determined
pH: Not available
Melting Point: 48–53°C
Boiling Point: Data not readily available, decomposes before boiling
Flash Point: Not readily flammable
Evaporation Rate: Not determined
Flammability: Not flammable under standard conditions
Vapor Pressure: Low, negligible under ambient conditions
Solubility: Poorly soluble in water, soluble in organic solvents such as acetone or DMSO
Density: ~2.2 g/cm³
Partition Coefficient (log Kow): Not available
Decomposition Temperature: Tends to decompose under strong heating
Viscosity: Not applicable as a solid
Chemical Stability: Stable under standard storage and handling conditions, may decompose with heat or exposure to strong light
Reactivity: Can react with strong reducing agents, bases, and acids to release hazardous products
Hazardous Reactions: Yields toxic fumes such as iodine vapor and nitrogen oxides under fire or decomposition conditions
Incompatible Materials: Strong alkalis, strong acids, organic materials, combustible substances
Hazardous Decomposition Products: Iodine, hydrogen iodide, nitrogen oxides, possibly carbon oxides
Polymerization: Not known to polymerize
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Harmful if swallowed or inhaled, can irritate respiratory tract and mucous membranes
Skin Corrosion/Irritation: May cause redness or dryness after prolonged contact
Eye Damage/Irritation: Risk of severe eye irritation or pain
Sensitization: Not classified as a skin sensitizer based on available data
Chronic Effects: Long-term exposure may affect thyroid or central nervous system
Carcinogenicity/Mutagenicity: No data indicating carcinogenic or mutagenic risk in humans
Other Data: Toxicity data limited, handle with caution and avoid unnecessary exposure
Ecotoxicity: Highly toxic to aquatic life, potential to cause long-term effects in water environments
Persistence and Degradability: Slow to degrade in soil or water, persistent organic pollutant profile
Bioaccumulation: Possible due to iodine content and chemical stability
Mobility: Poorly soluble in water, likely to adsorb onto soil or sediment particles
Other Effects: Avoid uncontrolled release into environment, threatens aquatic organisms and secondary consumers
Waste Treatment Methods: Collect material and contaminated debris in sealed containers, label as hazardous waste
Recommended Disposal: Chemical incineration in controlled facility complying with regional regulations
Do Not: Discharge to surface water, drains, or unapproved landfill
Special Precautions: Use only trained personnel for disposal, document all transfer and destruction procedures
Container Disposal: Triple rinse, puncture, and dispose of in accordance with local guidelines
UN Number: 2811 (Toxic solid, organic, n.o.s.)
Proper Shipping Name: Toxic solid, organic, n.o.s. (Contains 2-Nitroiodobenzene)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III (Low danger)
Marine Pollutant: Classified as hazardous for aquatic environments
Transport Labels: Toxic, Environmentally Hazardous Substance symbol
Special Precautions: Secure tightly, keep container upright and dry, inform carrier of hazards
TSCA Status: Listed in the United States Toxic Substances Control Act inventory
REACH Status: Subject to the European Union REACH regulation, may require registration
SARA Title III: Not listed as an extremely hazardous substance, but standard reporting required for toxic chemicals
California Proposition 65: Not identified on list as of latest update
WHMIS Classification: D2B (Toxic material causing other toxic effects, Canada)
Other Regulations: Subject to national and international chemical control measures regarding storage, labeling, and handling
Workplace Labeling: Use GHS-compliant precautionary and hazard statements on containers and storage rooms
