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Product Name: 2-Nitrobenzohydrazide
Chemical Formula: C7H7N3O2
CAS Number: 34846-43-6
Synonyms: o-Nitrobenzohydrazide
Recommended Use: Laboratory reagent, intermediate for organic synthesis
Manufacturer Information: Contact information of the supplier is essential for emergencies and support during unusual circumstances at any site utilizing this chemical. Immediate access to phone numbers and addresses helps reduce confusion during an incident.
GHS Classification: Acute toxicity (oral, dermal, inhalation), Eye irritant, Skin irritant
Signal Word: Warning
Hazard Statements: Harmful if swallowed, harmful in contact with skin, causes skin and serious eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust or vapors, wear protective gloves, eye protection, and clothing, wash hands thoroughly after handling, do not eat, drink or smoke during use, use only outdoors or in a well-ventilated area
Health Hazards: Inhalation causes respiratory discomfort, skin and eye contact leads to irritation and redness, ingestion results in nausea or abdominal discomfort
Environmental Hazards: Spillage risks contamination of soil and water, toxic to aquatic organisms even in low quantities, may disrupt ecological balance near release spots
Label Elements: Hazard pictograms for exclamation mark and health hazard appear on packaging and containers for visual alerts
Chemical Identity: 2-Nitrobenzohydrazide
Concentration: >98% pure
Impurities: Minor traces of byproducts from synthesis, information provided by the supplier
Molecular Weight: 165.15 g/mol
Relevant Identifiers: Specific CAS and EC numbers listed on safety sheets for cross-reference with government regulations and chemical suppliers
Inhalation: Move affected person away from exposure area into fresh air, allow free breathing, seek medical attention if breathing becomes difficult or symptoms persist
Skin Contact: Remove contaminated clothing, wash skin gently but thoroughly with plenty of water and soap, persistent irritation calls for medical attention
Eye Contact: Rinse immediately with flowing water for 15 minutes while holding eyelids open, seek medical supervision if irritation or vision changes remain
Ingestion: Do not induce vomiting, rinse mouth with water, get prompt medical care if symptoms like nausea, headache, or stomach pain develop
Most Important Symptoms: Redness, swelling, burning sensation reported in brief exposures; longer or repeated exposures can bring on dermatitis or respiratory troubles
Advice for Medical Professionals: Symptomatic treatment recommended, monitor exposure symptoms closely, consult poison control resources in complex cases
Suitable Extinguishing Media: Use water spray, dry chemical powder, foam, or carbon dioxide methods depending on surrounding materials and hazard assessment
Unsuitable Media: Direct, forceful water streams can spread contaminated materials and fuel the fire
Hazardous Combustion Products: Irritant and toxic fumes including nitrogen oxides, carbon monoxide, possible benzene derivatives
Protective Equipment for Firefighters: Self-contained breathing apparatus, full body chemical protection gear, boots and gloves
Fire Fighting Procedures: Isolate area to keep unauthorized personnel away, ventilate area post-incident, prevent water from entering drains or natural bodies
Personal Precautions: Evacuate non-essential persons, wear personal protective gear including gloves, goggles and suitable mask to prevent inhalation and skin absorption
Environmental Precautions: Contain spills with inert absorbent such as sand or earth, avoid sifting into soil or waterways, contact environmental agencies for major leaks
Methods for Cleaning Up: Scoop into secure, labeled container using non-sparking tools, clean contaminated area with soap and water, dispose waste according to local regulations
Special Instructions: Ventilate closed spaces, decontaminate tools with standard cleaning solutions, follow up with inspection to prevent residue remaining in workplace
Handling: Wear gloves, goggles and a laboratory coat every time 2-Nitrobenzohydrazide is handled, wash hands after contact, avoid dust and direct inhalation or ingestion
Storage: Keep in a tightly closed, labeled container away from food, incompatible substances, oxidizers and strong acids
Temperature Requirements: Store between 15-25°C in a cool, dry, well-ventilated place with minimal light exposure to protect chemical stability
Technical Measures: Use chemical fume hood or appropriate local exhaust, never store near sources of open flame, static electricity or direct sunlight
Storage Incompatibilities: Separate from oxidizers, acids, strong bases, store away from living quarters
Engineering Controls: Perform procedures in a fume hood, maintain proper ventilation, use explosion-proof electrical equipment if dust can form
Personal Protective Equipment: Nitrile gloves, chemical splash goggles, full laboratory coat, suitable dust mask or respirator in absence of proper ventilation
Hygiene Practices: Wash hands before breaks and at end of the workday, change out of contaminated clothing, regular surface cleaning to remove settled dust
Exposure Limits: Occupational exposure limit values for hydrazide compounds often apply, regular monitoring through workplace air sampling advised
Environmental Exposure Controls: Minimize emission through careful handling and immediate cleanup, never discharge untreated residues into sewage, drains, or open water
Appearance: Pale yellow crystalline powder
Odor: Slight chemical odor, not prominent
pH: Neutral to slightly acidic in water
Melting Point/Freezing Point: 180-184°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, solubility improves in ethanol and organic solvents
Flash Point: Data not established, exercise caution with high temperatures
Vapor Pressure: Negligible at ambient conditions
Density: Approximately 1.5 g/cm³
Partition coefficient (Log Pow): Not measured formally in literature but expected to be low due to polar groups
Explosive Properties: Not classified as explosive but dust deflagration possible under confined conditions
Oxidizing Properties: Not considered a strong oxidizer
Chemical Stability: Stable in original packaging under recommended storage and handling conditions
Conditions to Avoid: High temperatures, direct sunlight, open flames or hot surfaces; presence of strong acids, strong bases or oxidants
Incompatibility: Strong oxidizing agents, acids, bases, reducing agents increase risk of hazardous reactions
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, unknown organic vapors may form upon decomposition at high temperature
Polymerization: Not known to polymerize spontaneously under normal conditions
Acute Toxicity: LD50 in rats (oral) ranges 500-2000 mg/kg, causes nausea, dizziness, headache, abdominal pain if ingested
Skin Irritation: Direct contact generates moderate irritation, redness, possible swelling
Eye Irritation: Serious eye irritation, reddening, and tearing reported
Respiratory Sensitization: Dust inhalation can worsen pre-existing respiratory conditions
Skin Sensitization: Prolonged contact brings on allergic dermatitis in susceptible individuals
Chronic Effects: Repeated overexposure may affect blood and liver functions based on research into hydrazide derivatives
Symptoms of Exposure: Drowsiness, fatigue, headache, long-term contact could affect internal organs
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA, but structural similarities to known hazardous compounds call for ongoing care
Ecotoxicity: Harmful to aquatic organisms, risk of bioaccumulation is low but acute exposure may disrupt aquatic invertebrates
Mobility: Low vapor pressure and low solubility limit environmental distribution, but spills contribute to soil and surface water toxicity
Degradation: Chemical breaks down slowly under natural conditions, sunlight may help degrade on exposed surfaces
Bioaccumulative Potential: Not likely to bioaccumulate due to molecular structure, frequent monitoring required for compounds released into the open environment
Other Adverse Effects: Careless disposal or large-scale spills can damage local ecosystems, persist in soil, and affect microorganisms vital to soil health
Waste Disposal Methods: Dispose through a licensed chemical waste incinerator or officially approved hazardous waste facility; do not flush into sewer, surface water, or soil
Contaminated Containers: Treat empty packaging as hazardous, remove trace residues through approved chemical cleaning practices before recycling
Disposal Regulations: Follow local, national, and international environmental protection regulations. Always contact local regulatory authorities to verify correct and most up-to-date disposal guidance
Special Precautions: Record the amount and pathway of disposal, handle broken containers and residues in controlled zones to reduce occupational or environmental exposure
UN Number: Not officially assigned to 2-Nitrobenzohydrazide as of the last revision, treat as a potentially hazardous chemical in transit
Transport Hazard Class: Consult with carriers on packaging and labeling, class 6.1 (toxic substances) may be required
Packing Group: III as a precaution due to acute toxicity
Marine Pollutant: Not listed but treat as dangerous for water environments
Hazard Labels: Clearly display toxic and irritant signs, ensure documentation accompanies every shipment
Special Precautions: Keep away from incompatible substances and high temperatures during transport; use suitable containers, avoid rough handling, maintain record of quantities and destinations
EU Regulation (REACH): Not fully registered but falls under general chemical risk duty; safety assessment advised before large-scale use
U.S. Regulations: Subject to TSCA reporting and inventory standards, state and federal hazardous substance controls apply
Canada: Not listed as a domestic substance but included as a controlled product for workplace safety under WHMIS
Other International Inventories: Check specific requirements for labels, handling and reporting in every country of use
Workplace Labelling: Keep updated safety documentation, train staff, maintain visible and clear hazard labels on all primary and secondary containers
Community Right-to-Know: Maintain communication with local emergency services about locations, storage volumes, contact numbers in case of incident
