© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 5-Fluoro-2-Methylaniline
CAS Number: 367-30-6
Synonyms: 2-Amino-5-fluorotoluene, 5-Fluoro-o-toluidine
Recommended Uses: Chemical intermediates, research, pharmaceutical precursors
Supplier: Laboratory or industrial chemical supply companies
Contact Details: Refer to product label for emergency numbers and supplier address
Classification: Acute toxicity (oral, dermal, inhalation), skin irritation, eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, harmful in contact with skin, harmful if inhaled, causes skin and eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Do not breathe dust/fume/gas/mist/vapors/spray, wash hands thoroughly after handling, wear protective gloves/protective clothing/eye protection/face protection, use only outdoors or in a well-ventilated area, keep out of reach of children and unauthorized personnel
Chemical Name: 5-Fluoro-2-Methylaniline
Common Name: 5-Fluoro-o-toluidine
Chemical Formula: C7H8FN
Molecular Weight: 125.14 g/mol
Purity: Minimum 98% for lab-grade, technical grades may vary depending on manufacturer
Impurities: Trace aniline derivatives, halogenated byproducts (quantities typically <1%)
Inhalation: Move person to fresh air, support breathing with oxygen if breathing is difficult, consult physician if symptoms such as cough, dizziness, or throat irritation persist
Skin Contact: Wash immediately with plenty of water and soap for at least 15 minutes, remove contaminated clothing and shoes, seek medical attention if irritation or symptoms occur
Eye Contact: Rinse continuously with water for several minutes, keep eyelids open, remove contact lenses, obtain medical advice if redness or pain persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek urgent medical attention, provide information about chemical to healthcare providers
Most Important Symptoms: May cause headache, nausea, dizziness, respiratory discomfort, skin or eye irritation
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, water spray
Unsuitable Extinguishing Media: High-pressure water jets (may spread chemical), direct water stream (possible runoff hazard)
Hazardous Combustion Products: Nitrogen oxides, hydrogen fluoride, carbon monoxide, carbon dioxide, toxic organic vapors
Protective Equipment: Self-contained breathing apparatus, full protective firefighting gear
Advice for Firefighters: Isolate fire area, ventilate closed spaces before entering, cool surrounding containers with water spray, avoid inhaling combustion fumes
Personal Precautions: Wear chemical splash goggles, impervious gloves, lab coat or apron, avoid direct skin and eye contact, use respiratory protection if airborne dust or vapor is present
Environmental Precautions: Prevent release to drains, surface water, or soil, contain spill if safe to do so, avoid environmental contamination
Clean-Up Methods: Ventilate area, avoid dust formation, clean up with inert absorbent material (such as vermiculite or sand), collect into suitable, closed containers for disposal, wash spill area with water and detergent
Handling: Minimize contact with eyes, skin, and clothing, use with local exhaust or in a chemical fume hood, do not eat, drink, or smoke in areas where chemical is used, wash hands thoroughly after handling
Storage: Keep in tightly closed, labeled containers, store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers and acids, protect from physical damage, keep away from direct sunlight and heat sources, secure storage to prevent unauthorized access
Occupational Exposure Limits: No established exposure limits for this substance from OSHA, NIOSH, or ACGIH; minimize exposure as much as possible
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile or butyl rubber), safety goggles, laboratory coat, if risk of vapor formation is present use approved respirator with organic vapor cartridge
Hygiene Measures: Remove contaminated clothing and wash before reuse, wash hands after handling even if gloves are worn, do not touch face or eyes during use
Appearance: Pale yellow to brownish liquid or solid (depending on temperature)
Odor: Slightly aromatic, amine-like
Odor Threshold: Not available
pH: Not applicable (organic base, not water soluble enough for pH tested at neutral conditions)
Melting Point / Freezing Point: 5–10 °C
Boiling Point: 203–205 °C
Flash Point: 90–100 °C (Closed cup, approximate)
Evaporation Rate: Not determined
Flammability (solid, gas): May be combustible at high temperatures
Vapor Pressure: Low at ambient temperature (estimated 0.2 mmHg at 25 °C)
Vapor Density: >1 (air = 1)
Relative Density: 1.05 g/cm³ (approximate)
Solubility: Insoluble in water, miscible with alcohols and most organic solvents
Partition Coefficient (n-octanol/water): Estimated log Pow 1.75–2.1
Auto-ignition Temperature: Not available
Decomposition Temperature: Not available
Viscosity: Not available
Chemical Stability: Stable under normal conditions of storage and handling
Conditions to Avoid: Excess heat, open flames, direct sunlight, incompatible materials
Incompatible Materials: Strong oxidizing agents, strong acids, acid chlorides
Hazardous Decomposition Products: Under fire conditions, may emit toxic fumes of nitrogen oxides, hydrogen fluoride, carbon monoxide, and carbon dioxide
Polymerization: No dangerous polymerization expected
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Based on analogous aromatic amines and limited data, LD50 (oral, rat) estimated at 200–1000 mg/kg (toxic if swallowed), LD50 (dermal, rabbit) estimated above 1000 mg/kg (harmful in contact)
Irritation/Corrosivity: Causes skin and eye irritation, may cause respiratory tract irritation
Sensitization: Not enough information for assessment, aromatic amines may cause allergic reactions in rare cases
Chronic Effects: Prolonged or repeated exposure can damage liver, kidneys, blood, and possibly cause methemoglobinemia or carcinogenic effects (based on analogy to related compounds)
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA, but aromatic amines have been associated with carcinogenic risk in lab animals
Other Information: Target organ effects can include central nervous system, liver, and kidneys; symptoms may be delayed after exposure
Toxicity to Aquatic Life: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment, estimated EC50 (daphnia magna) in low mg/L range
Persistence and Degradability: Expected to be only partially biodegradable, aromatic amines tend to persist
Bioaccumulation Potential: Potential for moderate bioaccumulation based on log Pow estimate
Mobility in Soil: Limited data, moderately mobile in soil, possible ground water contaminant if large spill occurs
Other Adverse Effects: No data on ozone depletion, global warming, or photochemical ozone creation
Waste Treatment Methods: Collect and place in sealable chemical waste containers, do not allow into drains, waterways, soil, or public sewers
Disposal of Product: Dispose of through licensed chemical waste disposal contractor in accordance with local, regional, and national environmental regulations
Contaminated Packaging: Empty containers should be triple-rinsed and offered for reconditioning or disposed of as hazardous waste
Additional Information: Do not reuse containers, avoid contamination of municipal landfills, always report significant spills to regional environmental authorities if required
UN Number: Not specifically assigned, may be shipped as “Aromatic amine, liquid, n.o.s.” or similar
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains 5-Fluoro-2-Methylaniline)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III (low danger, but toxic)
Environmental Hazards: Classified as hazardous to aquatic environment
Special Precautions: Ensure cargo is secure and properly labeled, check vehicle or container ventilation, carry emergency procedures guide in transport
US TSCA Inventory: Not listed individually, check with supplier for exemption or notification status
REACH Status (EU): Not specifically registered, handle as a substance of concern
OSHA Hazard Communication: Hazardous chemical as defined by 29 CFR 1910.1200
SARA Title III: Not listed as an extremely hazardous chemical, not subject to Section 313 reporting, but general reporting may apply
Canadian Regulations: Listed on DSL/NDSL as part of chemical category; check supplier status
Other Global Regulations: Restrictions or labeling requirements vary by jurisdiction, always consult local and national regulations when importing, using, or disposing
