The story of 2-Cyclohexylbutane starts with the exploration of hydrocarbons decades ago, tracing roots back to the surge of petroleum chemistry in the mid-20th century. Chemists, curious about modifying saturated and branched hydrocarbon structures, identified cyclohexylalkanes as compounds with potential value in both research and industry. By the 1960s, the synthesis of substituted butanes gained traction as analytical tools improved. NMR and mass spectrometry delivered new ways to distinguish similar molecules. That progress made it easier to spot and separate 2-Cyclohexylbutane from its isomers, ultimately pushing its presence in chemical catalogs. Even though the molecule has mostly lived in the shadows compared to stars like benzene or ethylbenzene, researchers kept their eyes on its unique balance between ring and chain properties.
Many people in industry see 2-Cyclohexylbutane as a specialty molecule. Its up-front appeal seems modest, drawing interest among those hunting for performance additives or looking to dive into hydrocarbon skeletons for structure-activity studies. Chemists know cyclohexyl groups add a twist to otherwise simple butane chains, providing new physical parameters and a window to derivative creation. Despite being far from a household name, this molecule sneaks into various applications. Persistent curiosity and creative experimentation have kept it in the toolkit, prompting fresh looks with each passing decade.
Sitting between volatile solvents and dense oils, 2-Cyclohexylbutane illustrates how a cyclohexyl ring and a short aliphatic chain combine properties. The liquid is clear and oily under standard conditions. It usually brings a boiling point above straight-chain butanes, since the cycloalkane bulk boosts molecular weight and introduces steric effects. Its nonpolar nature prevents it from dissolving in water, but it readily mingles with organic solvents like hexane, ether, or toluene. The molecule’s resilience against acids and bases has unlocked roles in synthesis, and its hydrocarbon backbone limits reactivity, giving it staying power under mild lab conditions.
The technical world expects precision. On a bottle, you’ll spot the chemical name, CAS number, and purity, typically offered above 95%. Information about density and boiling range will help both bench chemists and plant operators handle and measure the right amounts. Labels urge users to store it sealed and away from ignition sources. Hazards—like flammability—appear in bold and pictograms don’t let anyone ignore potential risks. Regulations typically expect compliance with local and global GHS standards, but outside of industrial quantities, most shipments fall under generic hydrocarbon guidelines. Mistakes in handling are rarely forgiven, since hydrocarbon vapors present real dangers if ignored.
Laboratory routes to 2-Cyclohexylbutane draw from classic alkylation, Grignard reactions, and hydrogenation. One often combines cyclohexylmagnesium bromide with 2-chlorobutane or a similar halide to introduce the butyl group. Hydrogenation of 2-cyclohexyl-1-butene may offer another route, but needs robust control over temperature and pressure. Industrial pathways depend on consistent feedstocks, pure reagents, and cost-effective purification systems. As a chemist, I learned that purification becomes a challenge since byproducts and unreacted starting materials have similar boiling points. Fractional distillation under reduced pressure often stands as the method of choice when working at scale, demanding patience and vigilance from all involved.
The real value of 2-Cyclohexylbutane unfolds in its versatility for modification. With its saturated structure, it resists abrupt changes typical of aromatic systems, favoring slower, controlled transformations. Halogenation—especially under UV or with radical initiators—can attach functional groups. Careful oxidation can transform the butane chain or introduce ring changes, although finding a selective process means balancing reagents, time, and temperature. Researchers sometimes look to its backbone to anchor more elaborate fragments, using it as a scaffold for surfactants, lubricants, or as an inert carrier. For me, the main frustration lies in controlling selective functionalization. I have spent weeks chasing regioselectivity, only to run headlong into stubborn resistance or overreaction, a reminder that even “simple” hydrocarbons hide real synthetic puzzles.
Chemists often juggle multiple names for the same compound. In academic circles, 2-Cyclohexylbutane might turn up as simply “Cyclohexylbutane” or “Butane, 2-cyclohexyl-.” Systematic naming clears confusion, but traders and producers pick concise labels, often mixing shorthand and IUPAC rules. Purchasing agents and lab technicians need to check all these names to avoid mix-ups, as some catalog suppliers use historical or regional conventions. I’ve watched mistakes happen when subtle spelling or number differences led to months of work with the wrong reagent. The importance of double-checking each shipment can’t be overstated, especially with rare or unfamiliar molecules.
Hydrocarbons demand respect, and 2-Cyclohexylbutane follows suit. Flammability poses the main danger, especially if ventilation falters or sparks fly. Liquid splashes may cause skin or eye irritation, so decent gloves and goggles belong on the prep bench. Working near ignition sources or storing open containers risks disaster. Safe handling boils down to old habits: keep it cool, contain every spill, and never guess at labeling. Larger facilities invest in vapor detectors, strict maintenance schedules, and regular hazard drills. In the academic space, I have witnessed accidents that arose from ignoring precautions—reminders that even specialists must follow rules designed by experience, not just compliance checklists.
2-Cyclohexylbutane serves as a model compound in hydrocarbon research. Researchers study its thermal stability, look at its behavior in reaction mixtures, and test its performance as a phase-transfer medium or inert additive. Specialty lubricant developers value its balance between volatility and viscosity. Its bulky ring can modify the rolling and shear behavior in base oils. Explorers in surfactant and detergent chemistry test its modifications for impact on micelle formation. Pharmaceutical labs tinker with its structure, hoping to create new scaffolds for drug discovery, although its lack of reactive groups limits direct biological relevance. My first exposure came sorting through hydrocarbon samples for a catalysis study, learning that specialty molecules often end up making a difference in unexpected places—especially in fundamental research aimed at deciphering how structure impacts function.
Academic and industrial groups keep probing 2-Cyclohexylbutane for new uses. As advanced analytical tools have lowered the barrier to complex hydrocarbon research, interest in this molecule picks up. Catalysis screens, especially in petrochemicals, use it to test new metal complexes and zeolites, checking for unexpected activity or selectivity. Materials scientists glance its way for potential inclusion in specialty polymers or as plasticizer precursors, given the rigidity of the cyclohexyl ring. R&D teams always try to squeeze more function out of simple scaffolds, hoping a small tweak will deliver large gains in thermal stability, viscosity, or performance under extreme conditions. The steady flow of research papers on cyclohexyl alkanes shows scientists don’t shy away from revisiting classic molecules, especially when new insights can emerge.
With hydrocarbons, safety data speaks volumes. On 2-Cyclohexylbutane, researchers so far report little acute toxicity when exposure stays low and brief. Chronic data remains limited, although experience with similar cyclohexyl compounds—such as cyclohexane and other cycloalkyl derivatives—warns that inhalation over long periods can produce nervous system effects. The lack of polar groups means low reactivity with biological molecules, but that also allows slow elimination and possible accumulation through repeated exposure. Animal studies rarely go deep, while occupational health screens for hydrocarbons in general catch irregularities before they turn into major events. For those working directly with the material, regular ventilation checks, frequent training, and prompt spill response stick out as essentials. I recall the phrase an old lab manager liked to use: “Hydrocarbons are friendliest at arm’s length and with your eyes open.”
The journey of 2-Cyclohexylbutane looks far from over. Ongoing demand for novel base oils, custom solvents, and performance materials keeps this molecule in the running as a part of experimental blends. Organic chemists return to molecules like this when mapping new reaction pathways and hunting for selectivity or stability that simpler chains can’t deliver. Eco-friendly standards push some research in greener synthesis and degradable derivatives, and as analytical tools sharpen further, new properties may come to light. More environmental and health studies will fill in safety gaps. My own outlook draws from watching once-obscure chemicals become linchpins in new technologies and sustainable industries. Scientists who keep flexible minds and sharp eyes often take a second look at compounds like 2-Cyclohexylbutane—and sometimes, the next research leap depends on making the most out of these “background” molecules.
2-Cyclohexylbutane doesn’t make headlines, yet it plays a quiet role behind the scenes in many industries. Chemistry draws odd characters into the lineup—substances that may not seem important to most people, until you notice how often they're woven into modern life. I’ve spent a big chunk of my career digging through technical sheets, talking to industrial chemists, and piecing together the complex tapestry of where some of these compounds end up. 2-Cyclohexylbutane never struck me as a superstar, but it’s a steady workhorse for several chemical applications.
Most companies tapping into 2-Cyclohexylbutane see it as a reliable building block for more complex molecules. In the chemical industry, it’s used primarily as an intermediate. Sectors touching everything from specialty polymers to high-performance lubricants use it to tweak properties—changing viscosity or improving stability under pressure. I’ve crossed paths with several specialists in synthetic chemistry labs—many consistently cite compounds like 2-Cyclohexylbutane for their value in trial-and-error synthesis. They like it because it adds bulk and flexibility to molecular structures. That flexibility really matters in developing new solvent bases, custom rubbers, and even plasticizers found in cables and automotive parts.
The perfume and fragrance world sometimes glances in this direction too. Cycloalkyl compounds offer unique scent notes or help stabilize fragrance formulations. While it’s not the star performer in a perfumer’s toolkit, a compound like this might help in modulating consistency or balancing volatility in a new scent profile.
No discussion feels complete without safety. Any hydrocarbon brings risk, whether we’re talking flammability or toxicity. I’ve seen how poorly managed chemical stocks can lead to health issues or environmental trouble. Working in compliance training, I've stressed the importance of fresh air handling and adherence to exposure limits in workplaces messing with chemicals like this. Government agencies—OSHA, EPA—have guidelines in play, because even minor compounds can contribute to bigger pollution or health headaches if ignored. The wider public rarely thinks about these risks, but chemical workers know that proper labeling, hazard communication, and routine monitoring can make a difference.
One challenge comes down to scale. Specialty intermediates like 2-Cyclohexylbutane often ride the waves of demand for end-products. If a new polymer coating hits the market, demand may jump unexpectedly, pressuring smaller manufacturers who make these intermediates. I’ve talked with supply chain managers who groan about disruptions caused by missing shipments of “low-volume” chemicals. The lesson: so much of our chemical infrastructure depends on small links that remain invisible to most consumers.
Innovation thrives on flexibility. Next-generation materials depend on the right building blocks. Compounds like 2-Cyclohexylbutane, while obscure, support industries experimenting with biodegradable plastics, longer-lasting lubricants, and alternative fuel blends. My takeaway: the way we handle and prioritize these chemicals, from research to regulation, shapes everything from the safety of workplaces to the longevity of consumer products. Better traceability, smarter regulations, and open communication between suppliers and end-users all help prevent headaches—something anyone in the trenches of the chemical world can appreciate.
Most people don’t bump into 2-Cyclohexylbutane in daily life, but chemists and those in certain industries count on it for research and specialized manufacturing. Structurally, it’s a hydrocarbon, packing a cyclohexyl ring onto a butane backbone. This compound falls into the category of alkanes, and it doesn’t dabble much in reactivity under standard conditions. The molecule has a waxy, oily feel, and it’s clear and odorless, lacking the signatures you find with more reactive chemicals.
2-Cyclohexylbutane exists as a colorless liquid at room temperature, with a boiling point reaching above 200°C and melting below room temp. Its density lands pretty close to that of water, but because it’s nonpolar, it won’t mix with water — it floats on top, forming a neat layer. This quality makes it useful for applications that separate compounds based on polarity. You’ll find it dissolves well in organic solvents such as ether, chloroform, or acetone.
One key safety note: being an alkane, 2-Cyclohexylbutane is flammable. In any lab or industrial setting, good ventilation and fire prevention can’t be skipped. In my own chemistry lab days, ignoring the fire risk brought headaches and near-misses, especially during distillation or evaporation. Safety data sheets are worth reading, and storage in tightly sealed containers away from heat is a no-brainer, even if the liquid looks harmless.
As a saturated hydrocarbon, 2-Cyclohexylbutane sticks to its stable ways. Single bonds hold the structure together, lending resilience. You won’t see it participating in wild reactions the way unsaturated or aromatic compounds do. Without double or triple bonds, chemical reactivity sits on the low end, so oxidation and reduction don’t happen easily. That’s good news for stability but limits how often it steps into big reaction roles.
Chemically, one practical impact comes from this lack of reactivity. When I worked with saturated hydrocarbons, they rarely contaminated sensitive experiments, so they make effective media for storing reactive substances or acting as reference compounds in chromatography. 2-Cyclohexylbutane can serve as a calibration reference in analytical labs, where impurities would confuse expensive machinery and skew results.
Most outside of organic synthesis circles might ask why anyone cares about a chemically quiet hydrocarbon. One answer — its role in specialty solvents and comparative studies. With research funding tight, having reliable, stable hydrocarbons matters, since wildcards in the lab waste time. From petroleum studies to physical chemistry experiments, 2-Cyclohexylbutane helps benchmark how molecules behave under steady, predictable conditions.
Issues crop up in areas like storage and use. Flammable organics bring environmental and health risks, especially around open flames or sparks. I’ve seen old chemical stockrooms where poor labeling meant misplaced risk. Consistent labeling practices and regular chemical audits help keep everyone safe and the environment unharmed. Waste management calls for action, too, with spent hydrocarbons sent through special collection, not dumped down the drain.
At the manufacturing level, purity keeps processes consistent. Impurities change boiling points, throw off analytical readings, and sometimes trigger unwanted side products. Suppliers who focus on purity end up saving downstream users plenty of headaches. Instrument calibration in quality control labs relies on standard hydrocarbons like 2-Cyclohexylbutane. Getting sloppy here trickles down to problems in finished products.
Keeping safe storage practices and pushing for high-quality supply chains lines up with best practices not just for laboratories, but also for environmental and workforce health. Training, clear documentation, and frequent checks turn overlooked hydrocarbons into trusted tools. In the right hands, 2-Cyclohexylbutane plays its part, quietly supporting industries and labs that ask for dependability in every drop.
Ask anyone who has spent time in a lab or a chemical warehouse—complacency around chemicals gets people in trouble. I’ve seen folks rush tasks or cut corners because they thought they “knew their stuff.” That arrogance melts away after a spill or a scare. 2-Cyclohexylbutane, like other hydrocarbons, calls for respect and a focus on the basics. This isn’t just about checking off boxes on a safety sheet. Safe practices stem from creating habits and keeping a bit of healthy fear about what these products can do.
Every chemical has its personality, and 2-Cyclohexylbutane brings its own set of challenges. It’s flammable and can irritate skin or eyes. Health data shows that repeated exposure, especially to the vapors, can lead to headaches or dizziness. The reference to these real physical effects helps keep the hazards from feeling abstract. Once you’ve gotten a lungful of vapor or watched a poorly secured drum topple, you approach each bottle with more caution.
Label the container—not with some tiny code that only the record-keeper can interpret, but with a full name and hazard symbols. Clarity prevents mistakes. Store this chemical away from heat, sparks, and open flames. One quick look around a workshop tells you where those risks hide. A faulty outlet, a space heater, even static discharge can trigger disaster.
Ventilation matters more than most folks think. Vapors build up quickly in a closed space. Running a fume hood or keeping the drum in a ventilated cabinet means those fumes don’t hang around long enough to cause harm. I remember a “near miss” in a poorly ventilated storeroom—someone opened a drum and the vapor dropped him to his knees. Since then, I check for airflow every time.
Skin contact brings risk, so gloves rated for organic solvents form the first barrier. Goggles protect eyes from splashes; splashing happens more than people admit. Wearing a lab coat or apron adds another line of defense. Strong shoes help too, since dropping a container isn’t as rare as we’d hope.
Folks get tempted to skip masks, especially on quick jobs. But if you smell that sweet, hydrocarbon scent, the damage is already starting. Respirators fit for organic vapors keep those molecules out of lungs. Regular training goes hand in hand with gear—knowing how to check a mask’s fit or swap out a filter isn’t a given for everyone.
Knowing what to do when something spills creates confidence. Spill kits packed with absorbent pads, neutralizers, and disposal bags save time. A shower and eyewash station in arm’s reach can mean the difference between a minor scare and permanent injury.
Instead of assuming “it won’t happen to me,” good teams run drills. They know who grabs the spill kit, who sounds the alarm, who calls for help. Practicing response builds muscle memory, so panic never has time to set in. Too many times, I’ve seen someone hesitate and make the problem worse. Practice turns reaction into instinct.
Safe handling isn’t about following rules out of fear. The real goal: sending everyone home healthy at the end of the shift. Respecting chemicals, learning from close calls, and building solid habits all add up. That’s what I’d want if my family or friends worked down the hall.
Anyone can buy a drum of 2-Cyclohexylbutane, but only a smart operator stores and handles it without taking unnecessary chances. That mindset makes all the difference—every day, on every job.
Growing up in a small industrial city, I watched neighbors clock in at the local chemical plant. Safety rules didn’t always stick, and most folks counted on luck and tradition. The moment someone mentions a name like 2-Cyclohexylbutane, memories come rushing back: whiffs of strange odors, gloves tossed in a corner, warnings scribbled on old binders. Stories matter here, because chemicals follow people home—even if the factory gates close behind them at the end of the day.
To figure out the dangers, I started with the known facts. 2-Cyclohexylbutane belongs to a broad class of organic solvents—not the headline-grabbing variety that folks rally against, but still a hydrocarbon with red flags. Lab studies find it burns easily, releasing smoke loaded with off-gassing that brings sharp headaches and throat pain after just a few breaths too many. Chemical suppliers list it under “irritants,” especially if it touches skin or eyes. That makes sense. Skin isn’t a perfect shield. Most hydrocarbons sneak through, drying out natural oils or causing burns when workers forget long sleeves or safety goggles. Animal studies remain thin, but there are notes about mild toxicity after swallowing or sniffing higher doses in test animals. There’s no hard link yet to cancer, birth defects, or chronic illness, but new chemicals like this often hide their full story for years.
Spills concern me more. In college, creek water ran rust-orange after someone hosed out a barrel behind a warehouse. Fish floated belly up; turtles vanished. 2-Cyclohexylbutane doesn’t mix well with water, but traces hang around in soil and groundwater if nobody cleans up properly. It evaporates, rising into the air, and ends up in rivers or farmland after a summer rain. Aquatic life is far less forgiving than people, taking years to recover from brief contaminations. What the research suggests: even a single drum dump can harm fish, frogs, and insects for a long time. Drinking water near chemical plants can pick up traces, putting kids and older adults most at risk because of weaker immune systems.
The real problem comes from loose oversight. For every chemical like this, manufacturers give out safety sheets, but rules don’t always carry over to secondhand operations, scrapyards, or transport depots. Workers in smaller shops face shortages of proper gear. Masks break or run out. In many cases, folks rely on word of mouth, not formal training, to decide what feels safe. Regulators usually keep an eye on the big names, but smaller outfits can easily fall through the cracks.
Real solutions mean making protective gear non-negotiable, even if it slows things down. Companies could invest more in routine testing of air and soil if they keep 2-Cyclohexylbutane on site. Emergency plans for spills need practicing, not just paperwork. Building fences between clean water and chemical storage matters as much as locking up the storage tanks. Local health departments gain ground when they test for lesser-known chemicals during annual screenings. Sharing those results openly with the community lets everyone push back if air or water readings creep up. Chemical producers can publish real-world exposure studies, not just lab numbers. That’s information workers trust most, and it brings a human face to an issue often hidden behind chemical jargon.
People usually run into 2-Cyclohexylbutane in organic synthesis labs or in the catalogues of chemical suppliers. It's not something you’ll find in the back corner of a hardware store or on the average online marketplace. You need to dig through specialty chemical vendors, many of which focus on research, industry, or pharmaceutical clients.
Sites like Sigma-Aldrich, Fisher Scientific, ChemSpider, and Tokyo Chemical Industry list this kind of compound. Each of these sources asks for business verification. They don’t sell to walk-ins or hobbyists. For example, Sigma-Aldrich requires account setup, a business address, and background on intended use before they ship anything. For a lot of us who tinker or study chemistry, the price is sometimes just one part of a bigger challenge: eligibility to actually place an order.
The cost for 2-Cyclohexylbutane fluctuates depending on three things: purity, amount, and supplier. In one recent search, an American supplier listed 25 grams for about $180. If you’re scaling up, prices per gram drop, but big orders often demand additional paperwork and shipping fees—especially when shipping hazardous materials.
European and Asian suppliers occasionally offer lower prices per gram, but shipping, paperwork, and customs can wipe out any savings. Some places, especially in China, will post prices that look appealing at first glance, but that’s before you factor in freight charges or import requirements.
With so many chemicals, access depends partly on who you are. Laboratories, manufacturers, and universities get a smoother pathway. For regular people, legal restrictions stand in the way, especially since compounds like this sometimes show up on controlled lists in certain countries. Each chemical has its own set of rules depending on where you live and why you want it.
In my experience, even legitimate research sometimes stalls over paperwork. One professor once told me it took two months and three rounds of emails just to get approval from his university’s procurement office for a similar compound. Regulations help prevent misuse, but they also slow things down for those working on new materials or trying to scale up synthesis for a project.
It’s easy to forget about hidden costs when you hunt for rare chemicals. Shipping charges stack up rapidly. One time, a bottle worth $50 ended up costing $135 shipped because of hazardous material handling and insurance fees. Some suppliers tack on small-order surcharges if your total doesn’t meet their minimum buy.
Customs clearance can cause headaches, too, especially if the product lands in a country where it needs special paperwork. In regions with new regulations about chemicals, shipments get stuck for weeks, and buyers sometimes give up.
A few things make this easier. Always check local rules before buying. Have your end-use ready to explain—suppliers care about compliance and want to keep risk low. For researchers, working with institutional buyers or university purchasing offices saves time and hassle. Working through a purchasing department may add steps, but it brings legal safety and steadier communication with suppliers.
Talk to suppliers directly with questions about price, packaging, or documentation. They’ll usually send quotes quickly. For those determined to get hands-on with 2-Cyclohexylbutane, preparation beats shortcuts every day of the week.
| Names | |
| Preferred IUPAC name | 2-cyclohexylbutane |
| Other names |
2-Cyclohexylbutane Butane, 2-cyclohexyl- |
| Pronunciation | /tuː ˈsaɪ.kloʊ.hek.sɪl ˈbjuː.teɪn/ |
| Identifiers | |
| CAS Number | 1560-97-0 |
| Beilstein Reference | 3222145 |
| ChEBI | CHEBI:78143 |
| ChEMBL | CHEMBL2106386 |
| ChemSpider | 12673367 |
| DrugBank | DB14675 |
| ECHA InfoCard | 100.178.796 |
| EC Number | 262-203-7 |
| Gmelin Reference | 604873 |
| KEGG | C18757 |
| MeSH | D058723 |
| PubChem CID | 11668096 |
| RTECS number | GU8575000 |
| UNII | I2W4A6FWS5 |
| UN number | UN1993 |
| CompTox Dashboard (EPA) | DTXSID3058750 |
| Properties | |
| Chemical formula | C10H20 |
| Molar mass | 140.26 g/mol |
| Appearance | Colorless liquid |
| Odor | Odorless |
| Density | 0.857 g/mL at 25 °C (lit.) |
| Solubility in water | Insoluble in water |
| log P | 3.9 |
| Vapor pressure | 0.467 mmHg (25°C) |
| Acidity (pKa) | approximately 50 |
| Magnetic susceptibility (χ) | -70.72×10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.4542 |
| Viscosity | 0.925 cP (20°C) |
| Dipole moment | 0.13 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 378.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -176.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -4080.7 kJ/mol |
| Hazards | |
| GHS labelling | GHS02, GHS07 |
| Pictograms | C1CCC(CC1)CCCC |
| Signal word | Warning |
| Precautionary statements | P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378 |
| NFPA 704 (fire diamond) | 1-2-0 |
| Flash point | 64°C |
| Autoignition temperature | 225 °C |
| Explosive limits | Explosive limits: 1.1–6.7% |
| Lethal dose or concentration | LD50 (oral, rat): 3200 mg/kg |
| LD50 (median dose) | LD50 (median dose): 5 g/kg (rat, oral) |
| NIOSH | NIOSH: EO8225000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 200-800-2 |
| Related compounds | |
| Related compounds |
Cyclohexane Butane 2-Phenylbutane Cyclohexylmethane 2-Cyclohexylpropane |