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Understanding the Risks and Realities of 2-Chlorofluorobenzene: Beyond the Data Sheet

Identification

Chemical Name: 2-Chlorofluorobenzene
Synonyms: Ortho-chlorofluorobenzene
Chemical Formula: C6H4ClF
CAS Number: 367-21-5
Appearance: Colorless liquid with a distinct odor
Uses: Often used in the pharmaceutical and agrochemical industry as an intermediate or building block

Hazard Identification

Classification: Harmful if inhaled or ingested, skin and eye irritant
Label Elements: Flammable liquid, may cause respiratory irritation, toxic to aquatic life
Major health effects: Headache, nausea, dizziness, respiratory discomfort, skin redness
Warning pictogram: Exclamation mark, flame, environment symbol

Composition / Information on Ingredients

Main Ingredient: 2-Chlorofluorobenzene (purity typically exceeds 98%)
Impurities: Possible traces of related halogenated benzenes
Hazardous Components: No significant additives, most hazards stem from the main compound

First Aid Measures

Inhalation: Remove to fresh air, keep person at rest, medical help needed for breathing trouble
Skin Contact: Wash with soap and water, remove contaminated clothing, seek help for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove lenses, consult a doctor if irritation continues
Ingestion: Rinse mouth, get medical advice, do not induce vomiting
Special Note: Immediate attention helps minimize risk of delayed symptoms

Fire-Fighting Measures

Suitable Extinguishing Methods: Use foam, dry chemical, or carbon dioxide
Specific Hazards: Can produce toxic fumes like hydrogen chloride and hydrogen fluoride upon combustion
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing
Explosion Risk: Vapors may form explosive mixtures with air in confined spaces

Accidental Release Measures

Personal Precautions: Use personal protective equipment, avoid breathing vapors
Environmental Precautions: Prevent release into drains, soil, and waterways
Spill Cleanup: Absorb with inert material, ventilate area well, collect and dispose according to regulations
Further Steps: Wash contaminated area thoroughly

Handling and Storage

Safe Handling Tips: Use only in well-ventilated areas, avoid contact with skin and eyes
Storage Conditions: Store in tightly closed containers in a cool, dry place, away from sources of ignition or strong oxidizers
Incompatible Materials: Avoid storing with strong acids, bases, or oxidizing agents

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood or local exhaust
Personal Protection: Gloves made from nitrile, safety goggles, lab coat, use of a respirator in poorly ventilated spaces
Hygiene Measures: Wash hands and face before breaks and at end of work, no eating or drinking near materials
Occupational Exposure Limits: Not specifically established, but take standard organic solvent limits as a benchmark

Physical and Chemical Properties

Physical State: Liquid at room temperature
Color: Clear, colorless
Odor: Characteristic aromatic
Boiling Point: About 151°C
Melting Point: -35°C
Flash Point: 41°C (closed cup)
Solubility: Not soluble in water, miscible with most organic solvents
Vapor Pressure: Moderate at room temperature

Stability and Reactivity

Chemical Stability: Stable under standard handling and storage conditions
Reactivity: Can react with strong oxidizers and acids
Hazardous Decomposition: Produces hydrogen chloride and hydrogen fluoride gases under fire
Polymerization: Not known to polymerize spontaneously

Toxicological Information

Acute Toxicity: Moderate if inhaled or ingested, can irritate respiratory tract and digestive system
Skin / Eye Corrosion: Causes irritation and possibly burns on prolonged contact
Chronic Effects: Extended exposure may affect liver and kidney function, further studies ongoing
Symptoms: Dizziness, headache, skin redness, vomiting if swallowed in quantity

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms, may cause long-term damage in the environment
Persistence and Degradability: Largely resistant to biodegradation, can linger in soil and water
Bioaccumulative Potential: Moderate potential to bioaccumulate in the food chain
Other Hazards: Can affect local ecosystems if released in quantity

Disposal Considerations

Disposal Methods: Burn in proper chemical incinerator with scrubber, do not discharge into watercourses or public sewers
Container Handling: Empty containers should be triple-rinsed, punctured, and disposed at designated sites
Community Role: Encourage institutional and laboratory users to coordinate disposal efforts, prevent rogue dumping

Transport Information

UN Number: Classified among flammable liquids
Proper Shipping Name: 2-Chlorofluorobenzene
Transport Hazard Class: Flammable liquid
Packaging: Leakproof containers required, strong labels essential
Special Transport Rules: Avoid shaking, keep away from heat or sparks during transit

Regulatory Information

Labeling Requirements: Hazard and precautionary statements, clear hazard pictograms
Chemical Inventory Status: Included in major inventories across the US, Europe, and Asia
Workplace Laws: Strict ventilation, exposure measurements, reporting accidents as mandated by chemical safety acts
Community Right-to-Know: Compliance with disclosure guidelines helps public awareness