Chemical Name: 2-Butanone Oxime Common Synonyms: Methyl ethyl ketoxime, MEKO Chemical Formula: C4H9NO Physical Appearance: Clear to pale yellow liquid, strong characteristic odor CAS Number: 96-29-7
Main Hazards: Causes skin irritation, may cause allergic skin reaction, potential for respiratory irritation, suspected of causing cancer Routes of Exposure: Inhalation, skin contact, eye contact, ingestion GHS Classification: Acute toxicity – oral (Category 4), skin sensitization (Category 1), carcinogenicity (Category 2) Pictograms: Exclamation mark, health hazard symbol Signal Word: Warning
Component: 2-Butanone Oxime Concentration: >99% in most commercial applications Impurities: Trace levels of related ketoximes possible
Inhalation: Remove to fresh air, monitor breathing, provide oxygen if breathing becomes difficult Skin Contact: Rinse exposed area with water and soap for several minutes, remove contaminated clothing Eye Contact: Flush eyes with water for at least 15 minutes, seek medical attention Ingestion: Rinse mouth, do not induce vomiting, seek medical care immediately Symptoms: Irritation, headache, dizziness, possible allergic reaction on skin
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide Hazards in Combustion: Produces toxic fumes like nitrogen oxides and carbon monoxide Advice for Firefighters: Wear full protective gear and self-contained breathing apparatus Other Information: Ventilate closed spaces, contain runoff from firefighting to avoid pollution
Personal Precautions: Use protective equipment, avoid inhaling vapors, ensure proper ventilation Environmental Precautions: Prevent material from entering waterways, sewer systems, or soil Cleanup Methods: Absorb spill using inert materials, collect waste in suitable containers, ventilate area Decontamination: Wash contaminated surface with water and detergent, remove all clothing that made contact
Handling: Wear gloves and protective clothing, avoid breathing in vapors, work in well-ventilated spaces Storage: Store in a cool, dry, and well-ventilated location away from direct sunlight, protect containers from damage Segregation: Keep away from oxidizing agents Hygiene: Wash hands thoroughly after handling, avoid eating, drinking, or smoking in working areas
Engineering Controls: Use local exhaust ventilation, ensure general room ventilation Personal Protective Equipment: Chemical-resistant gloves, safety goggles, protective clothing Respiratory Protection: Use approved respirators if permissible exposure limits are likely to be exceeded Exposure Limits: Consult national occupational exposure limit values for guidance, some organizations recommend keeping airborne concentrations below 10 ppm
Physical State: Liquid Odor: Characteristic, ammonia-like Color: Clear to yellowish Boiling Point: Around 152°C Melting Point: -29°C Solubility: Soluble in water and most organic solvents Vapor Pressure: Moderate at room temperature Density: About 0.99 g/cm³ at 20°C
Chemical Stability: Remains stable under most recommended storage conditions Reactivity: Can react with strong acids, bases, oxidizing agents Decomposition Products: Produces harmful gases like carbon monoxide, nitrogen oxides if heated or burned Incompatibility: Avoid contact with peroxides, strong reducing and oxidizing agents
Acute Effects: Inhalation can cause dizziness or headaches, skin absorption may contribute to systemic toxicity Chronic Effects: Reports link repeated exposure to organ damage, possible increase in cancer risk Sensitization: Can trigger skin sensitization in susceptible individuals LD50 (Oral, Rat): Around 930 mg/kg Irritation: Causes eye, nose, and throat irritation on contact or high vapor concentrations
Aquatic Toxicity: Harmful to aquatic organisms, long-term adverse effects in the aquatic environment Persistence and Degradability: Slowly degradable in soil and water, may persist in some conditions Bioaccumulation: Not likely to bioaccumulate significantly Precautions: Prevent release into waterways, as environmental exposure can have cumulative impacts
Waste Handling: Collect and transfer waste for disposal at licensed hazardous waste facilities Disposal Methods: Prefer incineration under controlled conditions to prevent atmospheric release Never pour into drains, sewers, or on soil surfaces Packaging Disposal: Triple rinse empty containers, dispose of as hazardous waste Regulations: Reference local, regional, and national legislation for chemical waste
Transport Classification: Classified as a hazardous material for most shipping routes, including road, rail, air, and sea Packaging Requirements: Use approved, tightly sealed containers, label appropriately Precautions: Minimize movement and secure containers to prevent leaks Regulatory Notes: Check compliance with International Air Transport Association and International Maritime Dangerous Goods regulations for classification specifics
Global Listings: Addressed by multiple regulatory agencies due to its health hazard profile Control Regulations: Included in several workplace safety, environmental, and chemical management frameworks Restrictions: May face supply and use restrictions in some countries due to carcinogenicity concern Worker Protection: Occupational exposure standards published in some national guidelines, highlighting the importance of PPE and monitoring Community Right-to-Know: Facilities that store or use significant amounts often must report their inventories for public safety transparency