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Material Safety Data Sheet: 2-Bromophenol

Identification

Chemical Name: 2-Bromophenol
Synonyms: o-Bromophenol, ortho-Bromophenol
CAS Number: 95-56-7
Product Number: Provided by manufacturer
Recommended Uses: Organic synthesis, research
Supplier: Manufacturer or distributor contact information
Emergency Phone Number: Accessible via supplier

Hazard Identification

Hazard Classification: Acute toxicity, Skin/eye irritation, Aquatic hazard
GHS Label Elements: Signal word: Warning
Pictograms: Exclamation mark, environmental hazard
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, toxic to aquatic life, may cause respiratory irritation
Precautionary Statements: Avoid contact, wash skin thoroughly after handling, avoid release to environment

Composition / Information on Ingredients

Substance: 2-Bromophenol
Chemical Formula: C6H5BrO
Concentration: 100% (pure substance)
Impurities: Trace organic compounds depending on source
EC Number: 202-417-0

First Aid Measures

Inhalation: Move person to fresh air, offer oxygen if breathing is difficult, seek medical attention if symptoms appear
Skin Contact: Remove contaminated clothing, wash affected area with soap and water for at least 15 minutes, get medical advice if irritation persists
Eye Contact: Flush eyes with water for several minutes, remove contact lenses if present, seek medical help
Ingestion: Rinse mouth, drink water if conscious, do not induce vomiting, call medical services immediately
Most Important Symptoms: Irritation, headache, dizziness, nausea
Notes for Physician: Treat symptomatically

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam
Unsuitable Media: Water jets
Specific Hazards: May release toxic fumes such as bromides and phenolic compounds under fire conditions
Protective Equipment for Firefighters: Self-contained breathing apparatus, full fire resistant clothing
Special Precautions: Avoid run-off from fire control; prevent entry to sewers or waterways

Accidental Release Measures

Personal Precautions: Avoid breathing vapors, use personal protective equipment, avoid skin and eye contact
Environmental Precautions: Do not allow entry into waterways, drains, soil
Cleanup Methods: Absorb with inert material like sand, seal in container for disposal, ventilate area, wash residues with water

Handling and Storage

Precautions for Safe Handling: Wear protective gear, work in fume hood, avoid inhalation and direct contact
Conditions for Safe Storage: Store in cool, dry, well-ventilated area away from incompatible substances, use tightly sealed containers, avoid sunlight and sources of ignition
Incompatibilities: Strong oxidizers, strong bases

Exposure Controls and Personal Protection

Occupational Exposure Limits: Not established specifically for 2-Bromophenol, handle with general laboratory precautions
Engineering Controls: Use chemical fume hood, use proper ventilation
Personal Protective Equipment: Chemical safety goggles, gloves resistant to chemicals, lab coat, in some cases face shield and respiratory protection
Hygiene Measures: Wash hands after handling, no eating or drinking in work area

Physical and Chemical Properties

Appearance: White to off-white crystalline solid
Odor: Phenolic
Molecular Weight: 173.01 g/mol
Melting Point: 65–69 °C
Boiling Point: 223–224 °C
Solubility: Moderately soluble in water, soluble in organic solvents
pH: Slightly acidic in aqueous solution
Density: 1.736 g/cm³ at 20 °C
Vapor Pressure: Low at room temperature
Flash Point: 110 °C (closed cup)
Auto-ignition Temperature: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong oxidizing agents
Hazardous Reactions: None expected under normal handling
Conditions to Avoid: Heat, sparks, open flames, incompatible materials
Decomposition Products: Bromine compounds, phenol derivatives, carbon monoxide, carbon dioxide

Toxicological Information

Acute Toxicity: Harmful if swallowed, may cause respiratory system irritation
Skin Corrosion/Irritation: May cause irritation, redness, discomfort
Serious Eye Damage/Irritation: Risk of irritation, tearing, redness
Respiratory Sensitization: May cause irritation to respiratory tract
Ingestion Effects: Nausea, vomiting, abdominal pain, symptoms may include dizziness
Chronic Effects: No chronic toxicity known in humans under standard lab use
Carcinogenicity: Not classified as carcinogen by IARC, NTP, ACGIH, OSHA
Mutagenicity: No conclusive data for mutagenic potential
Other Effects: Repeated or prolonged exposure may cause skin or respiratory irritation
LD50 (Oral - Rat): 980 mg/kg (literature value)

Ecological Information

Aquatic Toxicity: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, may persist in environment
Bioaccumulation Potential: May bioaccumulate depending on environmental conditions
Mobility in Soil: Moderate mobility, depends on soil type
Other Adverse Effects: Can impact local ecosystems if released

Disposal Considerations

Waste Disposal: Dispose of as hazardous chemical waste per local, state, federal guidelines
Contaminated Packaging: Treat containers as hazardous, triple rinse, dispose via licensed waste contractor
Precautions: Do not flush into surface water, avoid release to environment

Transport Information

UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 2-Bromophenol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Transport Label Required: Toxic, environmental hazard

Regulatory Information

SARA Title III, Sections 302/304: Not listed
SARA Title III, Section 313: Not subject to reporting
TSCA (Toxic Substances Control Act): Listed
REACH: Registration required in Europe above threshold volumes
WHMIS Classification: D2B (Toxic material causing other toxic effects)
California Proposition 65: Not listed as known carcinogen or reproductive toxin
Other local, national, or regional regulations: Consult respective authorities