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Chemical Name: 2-Aminophenol Hydrochloride
Other Names: o-Aminophenol Hydrochloride, 2-Hydroxyaniline Hydrochloride
CAS Number: 600-22-6
Molecular Formula: C6H8ClNO
Molecular Weight: 145.59 g/mol
Recommended Use: Used in dye manufacturing, chemical research, and as an intermediate in pharmaceuticals.
Supplier Contact: Emergency phone numbers and responsible party details provided by supplier.
Classification: Harmful if swallowed, causes skin and serious eye irritation, may cause respiratory irritation.
Signal Word: Warning
Hazard Statements: H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
Pictograms: Exclamation mark (GHS07).
Precautionary Statements: Avoid breathing dust. Wear protective gloves and eye protection. Wash thoroughly after handling. Do not eat, drink, or smoke while working with this compound.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact.
Substance: 2-Aminophenol Hydrochloride
Purity: >98%
Impurities: Trace organic and inorganic material below 2%.
Component Risks: Significant health hazards mainly due to amine functional group and hydrochloride salt contributing to corrosive properties.
Inhalation: Move the person to fresh air immediately. Seek medical attention if symptoms develop or persist.
Skin Contact: Remove contaminated clothing and rinse skin with plenty of water for at least 15 minutes. If irritation appears or persists, consult a physician.
Eye Contact: Flush eyes with running water for several minutes while holding eyelids apart. Remove contact lenses and continue rinsing. Get medical help immediately.
Ingestion: Rinse mouth thoroughly and drink water if person is conscious. Never give anything by mouth to an unconscious person. Urgent medical treatment required.
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, or carbon dioxide.
Unsuitable Extinguishing Media: Direct water jet (can spread contaminated material).
Hazardous Combustion Products: Emits toxic vapors including nitrogen oxides, hydrogen chloride, carbon monoxide.
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Special Hazards: Risk of hazardous fumes if involved in fire, risk of dust explosion with finely divided product.
Personal Precautions: Avoid skin and eye contact. Use proper ventilation. Wear suitable protective gear.
Environmental Precautions: Do not allow spillage to enter drains or water courses. Contain runoff to prevent soil contamination.
Methods for Cleanup: Sweep up or collect material and place in a suitable container for proper disposal. Rinse contaminated area with water, avoiding dust formation.
Emergency Procedures: Evacuate non-essential personnel. Isolate area if large spill occurs.
Handling: Always use with adequate ventilation or under a chemical fume hood. Wear protective gloves, goggles, and lab coat. Wash hands after handling. Avoid inhalation and direct contact with powder.
Storage: Store in a tightly sealed container, in a cool, dry, well-ventilated location away from incompatible substances such as strong oxidizers, bases, and acids. Avoid moisture exposure. Keep away from food and beverages.
Exposure Limits: No occupational exposure limits established by OSHA, ACGIH for this compound; handle as potentially hazardous.
Engineering Controls: Use fume hoods or appropriate local exhaust to minimize exposure.
Personal Protective Equipment: Chemical safety goggles, gloves resistant to chemicals, laboratory coat, and, if dust risk exists, use respiratory protection.
Hygiene Measures: Remove and wash contaminated clothing before reuse. Do not eat, drink, or smoke during use.
Appearance: Off-white to yellowish crystalline powder.
Odor: Faint, characteristic.
Melting Point: 215-220°C (decomposes).
Boiling Point: Not applicable (decomposes before boiling).
Solubility: Soluble in water; slightly soluble in ethanol.
pH (1% solution): Approximately 4-5.
Density: 1.378 g/cm³.
Vapor Pressure: Not determined.
Other Properties: Stable under recommended storage, sensitive to moisture.
Chemical Stability: Stable under ordinary conditions with dry storage.
Incompatible Materials: Strong oxidizing agents, strong bases, acids, avoid moisture.
Hazardous Reactions: Decomposes on heating to produce corrosive and toxic gases including hydrogen chloride and nitrogen oxides.
Conditions to Avoid: Elevated temperature, exposure to moisture, open flames.
Acute Toxicity: Harmful if swallowed; LD50 (oral, rat) data in range of 300-2000 mg/kg.
Skin Contact: Causes irritation; prolonged exposure may cause dermatitis.
Eye Contact: Causes serious irritation, redness, pain.
Inhalation: May cause nose, throat, and lung irritation; high dust concentrations aggravate symptoms.
Sensitization: No conclusive data supporting skin or respiratory sensitization.
Chronic Effects: Repeated exposure can produce similar symptoms to acute effects. Not listed as carcinogen by IARC, NTP, or OSHA.
Aquatic Toxicity: Harmful to aquatic organisms in concentrated form. May cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Readily biodegradable under aerobic conditions.
Bioaccumulation Potential: Low; does not significantly build up in aquatic organisms.
Mobility in Soil: Moves readily in moist soils but degrades relatively quickly.
Disposal Methods: Dispose as hazardous chemical waste in accordance with local, regional, and national environmental regulations.
Prohibited Disposal: Do not release into drains, soil, or natural waters.
Contaminated Packaging: Rinse empty containers with copious water before disposal.
UN Number: Not regulated under UN recommendations.
Proper Shipping Name: 2-Aminophenol Hydrochloride
Transport Hazard Class: Not classified as hazardous for transport under ADR/RID, IMDG, IATA.
Packing Group: Not applicable.
Special Precautions: Avoid package damage and moisture during transit.
Inventory Status: Listed on chemical inventories (EINECS, TSCA, DSL, etc.)
Labeling Requirements: GHS labels including hazard and precautionary statements.
OSHA Hazard Communication: Classified as hazardous according to OSHA standards.
SARA Title III: Not subject to specific reporting.
California Proposition 65: Not listed.
Other Regulations: Conforms to European REACH classification guidelines and domestic chemical control legislation where applicable.
