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2,5-Dichloroaniline: Looking at the MSDS Details Up Close

Identification

Chemical Name: 2,5-Dichloroaniline
Synonyms: 2,5-DCA
Molecular Formula: C6H5Cl2N
Appearance: Pale yellow solid, characteristic odor
CAS Number: 95-82-9
Common Usage: Used in dye and pigment industries, intermediate for pesticides, and chemical research

Hazard Identification

Hazard Classifications: Acute toxicity, skin and eye irritant
Pictogram: Exclamation mark, health hazard
Signal Word: Warning
Main Hazards: Harms skin and eyes, breathing in dust or vapors irritates the airways, causes headaches and nausea, long-term exposure may impact liver and kidney function, dangerous to aquatic animals and water systems

Composition / Information on Ingredients

Component: 2,5-Dichloroaniline
Concentration: Typically over 98 percent by weight
Impurities: Trace amounts of related anilines, potential residual solvents from processing

First Aid Measures

Skin Contact: Take off heavily contaminated clothing, wash area with lots of cool water and mild soap, keep washing for several minutes
Eye Contact: Hold eye open, rinse with gentle stream of water for at least fifteen minutes, remove contact lenses if present
Inhalation: Move to fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms show up
Ingestion: Rinse mouth, do not cause vomiting, seek immediate medical attention

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide for small fires; water spray for larger fires
Specific Hazards: Releases chlorine compounds, nitrous gases, and hydrogen chloride when burning
Protective Equipment: Full protective clothing and self-contained breathing apparatus recommended for responders
Fire Behavior: Dust may form explosive mixtures with air; steam or smoke from a fire gets toxic quickly

Accidental Release Measures

Personal Precautions: Use chemical-resistant gloves, goggles, and a suitable respirator
Environmental Precautions: Stop product from entering drains, waterways, or soil
Cleanup Methods: Scoop spilled product into secure chemical containers, clean surfaces with water and mild detergent, ventilate area

Handling and Storage

Handling: Work in well-ventilated areas, avoid breathing dust or vapor, minimize contact with skin and eyes, never eat or drink near product
Storage: Keep containers tightly closed, store in cool, dry, well-ventilated spot away from strong acids, oxidizers, and sunlight to preserve chemical stability

Exposure Controls and Personal Protection

Engineering Controls: Fume hoods, local exhaust systems, and sealed processes reduce risk, keeping air clear of hazardous dust
Personal Protective Equipment: Nitrile gloves, chemical splash goggles, laboratory coat or protective garment, appropriate respirator if ventilation proves inadequate
Exposure Limits: Refer to established occupational exposure guidelines such as ACGIH or OSHA for amines, even though no clear standard covers every substituted aniline

Physical and Chemical Properties

Appearance: Pale yellow, crystalline or solid block
Odor: Distinct amine scent
Melting Point: 63 to 65 °C
Boiling Point: 267 °C
Density: About 1.4 g/cm³
Solubility: Low in water, soluble in ethanol, benzene, and other organic solvents
Vapor Pressure: Low at room temperature
Flash Point: Over 110 °C (closed cup)

Stability and Reactivity

Chemical Stability: Stable if kept cool, dry, and in tightly sealed containers
Reactivity: Reacts with strong acids, oxidizing agents, and halogens; forms unstable byproducts in strongly acidic or basic settings
Hazardous Decomposition Products: Gives off toxic fumes of nitrogen oxides, hydrogen chloride, and chlorinated organics at high temperature or if mixed with certain chemicals

Toxicological Information

Acute Effects: Eyes and skin sting or redden after contact; breath shortens and coughing starts with dust inhalation; headaches and nausea sometimes appear
Chronic Effects: Long exposure ties to liver and kidney issues, methemoglobinemia (reduces blood’s ability to hold oxygen), animal studies suggest possible cancer risk
Routes of Entry: Skin contact, inhalation, accidental swallowing
Notable Symptoms: Blue-tinted skin or lips, nervous system changes, chronic fatigue for regular handlers

Ecological Information

Environmental Fate: Lingers in soil and water, does not easily break down under normal conditions
Aquatic Toxicity: Harms fish and small invertebrates at low concentrations
Bioaccumulation: Accumulates in fish tissue, passes through food chain
Degradability: Decomposes only slowly, often through specialized bacteria or sunlight-driven processes

Disposal Considerations

Disposal Methods: Must be sent for specialized hazardous waste treatment, incineration under controlled conditions preferred
Container Handling: Rinse drums or bottles thoroughly, destroy or recycle only by authorized handlers
Legal Restrictions: Regulations control release to landfills, water streams, or ordinary trash based on local hazardous waste rules

Transport Information

UN Number: UN 2564 (for 2,5-dichloroaniline in pure or well-defined mixtures)
Transport Class: Class 6.1 (toxic substances)
Labels: Toxic, environmental hazard
Packaging Requirements: Leak-proof, impact-resistant drums or secure chemical bottles, labeled according to hazard class
Transport Precautions: Prevent package rupture, keep away from food and animal feed in storage or transit vehicles

Regulatory Information

Global Restrictions: Listed under several national and global toxic substance controls, presence triggers reporting to environmental protection agencies
Workplace Safety Standards: Employers must provide hazard training and protective gear, meet ventilation and exposure requirements
Labeling: Requires GHS pictograms, signal word, and hazard statements in shipping and workplace settings
Chemical Inventory: Included in lists like TSCA (USA), REACH (EU), and similar control programs across Asia-Pacific and Americas