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2,4-Dibromoaniline: A Down-to-Earth Look at Material Safety

Identification

Chemical Name: 2,4-Dibromoaniline
Chemical Formula: C6H5Br2N
CAS Number: 615-92-7
Physical Appearance: Off-white to pale yellow solid or crystalline powder
Odor: Faint aromatic or amine-like scent
Common Uses: Used in research labs, as a building block in organic synthesis, and for dye or pesticide development

Hazard Identification

Risk Pictograms: Acute toxicity, skin and eye irritant
Health Hazards: Exposure can irritate skin, eyes, and the respiratory tract
Chronic Risks: Repeated contact may cause skin dryness; breathing dust can harm lungs
Sensitization: May trigger allergic reactions after skin contact in sensitive individuals
Environmental Danger: Harmful to aquatic life if released into streams or soil run-off
GHS Classification: Harmful if swallowed, causes serious eye irritation, may cause respiratory irritation

Composition / Information on Ingredients

Main Component: 2,4-Dibromoaniline, over 98% purity
Impurities: Typically contains trace brominated or aminated aromatic compounds

First Aid Measures

Inhalation: Remove person to fresh air, keep at rest, offer medical attention if breathing becomes troubled
Skin Contact: Wash area thoroughly with soap and water, do not scrub too hard to avoid causing further irritation
Eye Contact: Rinse cautiously with water for several minutes, lift eyelids to wash underneath, seek medical attention if discomfort persists
Ingestion: Rinse mouth, never induce vomiting, seek prompt medical evaluation if large amounts swallowed

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, or carbon dioxide
Special Hazards: Thermal decomposition releases toxic fumes of hydrogen bromide, nitrogen oxides
Protective Equipment: Firefighters should use full protective gear and self-contained breathing apparatus
Other Notes: Avoid water runoff contacting sewers or waterways; residue might be hazardous

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, dust mask or respirator
Spill Cleanup: Use non-sparking tools, sweep up without generating dust, place in clearly labeled shut container for disposal
Ventilation: Open windows or use exhaust fan to keep dust from lingering
Environmental Caution: Avoid letting product move into drains or water supplies

Handling and Storage

Handling: Keep container tightly closed, avoid generating or breathing dust, avoid eating, drinking, or smoking while working with the compound
Hygiene: Wash hands thoroughly after handling, change contaminated clothing
Storage: Store in a cool, dry, well-ventilated room away from heat sources, sunlight, oxidizing agents, acids and incompatible chemicals

Exposure Controls and Personal Protection

Engineering Controls: Fume hood or local exhaust recommended where dust or vapor might occur
Personal Protection: Protective gloves made of nitrile or neoprene, chemical splash goggles, lab coat, NIOSH-approved dust respirator
Work Practices: Avoid skin contact, avoid inhaling particles, keep working area clean
Exposure Limits: No established occupational exposure limits for 2,4-Dibromoaniline, but minimize dust concentration in line with general good laboratory practice

Physical and Chemical Properties

Form: Solid, crystalline
Color: Off-white to light yellow
Boiling Point: Approximately 308–310 °C
Melting Point: About 76–80 °C
Density: Around 2.0 g/cm³
Solubility: Slightly soluble in water; dissolves in ethanol, ether, and most organic solvents
Vapor Pressure: Very low under ambient conditions
Odor Threshold: Not well defined
pH: Not applicable as a solid

Stability and Reactivity

Chemical Stability: Stable under normal temperature and pressure, keep away from moisture
Incompatibilities: Strong oxidizers, acids, acid chlorides, anhydrides
Hazardous Decomposition: Generates toxic fumes of hydrogen bromide, nitrogen oxides if heated strongly
Polymerization: No hazardous polymerization reported

Toxicological Information

Acute Toxicity: Swallowing or breathing high levels can cause headache, nausea, irritation
Skin and Eye Effects: Irritation, redness, may cause rash in susceptible people
Long-Term Exposure: Chronic exposure not well studied, but aromatic amines as a whole linked to organ and genetic risks
Carcinogenicity: No conclusive human data, but many related compounds have caused concern in animal studies

Ecological Information

Mobility: Not very water-soluble; tends to bind to soil and sediment
Persistence: Does not biodegrade readily under typical conditions
Bioaccumulation: Has potential to build up in aquatic wildlife due to poor breakdown
Aquatic Toxicity: Highly toxic to aquatic organisms, disrupts fish and insect development

Disposal Considerations

Waste Management: Treat as hazardous chemical waste; use licensed waste service
Disposal Methods: Do not pour down the drain or throw in regular trash, incinerate if possible in approved facility
Regulations: Follow local, state, and national rules on disposal of organobromine compounds

Transport Information

Shipping Classification: Usually not designated as a dangerous good for transport under standard U.N. codes, but always declare
Packaging: Sealed, clearly labeled containers suited for solids, avoid breakage and spills
Precautions: Keep away from food, feed, strong oxidants, and acids during loading and storage

Regulatory Information

Chemical Inventory Status: Registered on several international chemical lists
Regulatory Controls: Subject to environmental and workplace safety rules for handling and disposal, including restrictions in some countries for use or release
Worker Right-to-Know: Handling rules require notification and training for staff exposed to significant amounts
Labeling: Must be clearly identified as a hazardous substance with risk statements as per GHS