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Name: 2,4,6-Tribromoaniline
Chemical Formula: C6H4Br3N
Appearance: Pale yellow to tan crystalline powder, distinct chemical odor noticeable in concentrated forms
Common Uses: Intermediate in organic synthesis; laboratory research
CAS Number: 615-27-0
Acute Health Effects: May irritate skin, eyes, and respiratory tract upon contact or inhalation
Chronic Exposure Risks: Long-term exposure not studied extensively, caution warranted
NFPA Rating: Health: 2, Flammability: 0, Reactivity: 0 (standardized hazard scale for quick reference)
GHS Classification: Irritant category, caution for environmental persistence due to halogen content
Symptoms of Exposure: Redness, itching at contact site, coughing if inhaled, nausea if swallowed
Chemical Identity: Single component, 2,4,6-Tribromoaniline
Purity: Often found at >98% for research use
Impurities: Trace brominated byproducts possible if synthesis not complete
Inhalation: Move affected person to fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing immediately
Eye Contact: Rinse eyes cautiously with clean water for at least 15 minutes, seek ophthalmic evaluation for persistent irritation
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical care
Extinguishing Media: Use water spray, dry chemical, CO2, or foam; avoid strong jets of water
Fire-Related Hazards: May emit toxic fumes such as hydrogen bromide, nitrogen oxides if burned
Special Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing
Fire Response Advice: Evacuate area, limit spread of fumes when possible
Spill Response: Sweep up and collect spilled material carefully, avoid dust generation
Containment: Prevent entry to drains, sewers, or water bodies
Cleanup: Ventilate spill area, wipe down with damp cloth, use dedicated equipment for cleanup
Personal Protection: Wear gloves, goggles, dust mask or respirator
Handling: Maintain good housekeeping, keep container tightly closed during use, avoid creating dust
Personal Precautions: Use gloves and protective eyewear, wash hands after handling, keep food and beverages away from work area
Storage Conditions: Store in cool, dry, well-ventilated space, away from incompatible chemicals such as oxidizers and strong acids
Container Materials: Use glass, HDPE, or compatible chemical-resistant materials
Exposure Limits: No established occupational exposure limits, exercise caution and minimize exposure
Engineering Controls: Fume hood or local exhaust encouraged
Personal Protective Equipment: Chemical-resistant gloves, goggles or face shield, lab coat, and particulate mask or respirator for dust
Hygienic Practices: Change out of contaminated clothing promptly; thoroughly wash before leaving work
Molecular Weight: 345.83 g/mol
Melting Point: Reported range 145–148°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, soluble in organic solvents (e.g., ethanol, acetone)
Vapor Pressure: Negligible under ambient conditions
Density: Estimated around 2.5 g/cm³
Odor: Faint, chemical-like when pure
Chemical Stability: Stable under recommended storage, no rapid decomposition at room temperature
Reactivity: Non-reactive by itself under normal laboratory conditions
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition: Decomposes on heating, forming hydrogen bromide, carbon monoxide, carbon dioxide, nitrogen oxides
Acute Toxicity: Data limited, but based on related compounds, likely low to moderate acute oral and dermal toxicity
Skin/Eye Irritation: Risk of irritation, particularly to sensitive individuals
Allergic Reactions: No evidence for sensitization, though caution taken for halogenated aromatics
Chronic Effects: Lack of long-term exposure studies, prudent to avoid repeated contact
Aquatic Toxicity: Brominated aromatics often persist in water, potential for negative impact on aquatic life
Persistence/Degradability: Poorly biodegradable, may accumulate in sediments
Bioaccumulation: Likelihood moderate to high for similar halogenated organic chemicals
General Environmental Precautions: Prevent large releases to water, soil, or sewer systems
Waste Disposal: Incinerate in approved facility with proper controls to capture halogenated fumes
Hazardous Waste: Treat as hazardous chemical waste, never dispose of with ordinary trash or drains
Local Requirement Suggestion: Consult local, regional, and national rules for chemical disposal
Shipping Classification: Not classed as highly dangerous, but standard labeling for chemical hazard recommended
Transport Precautions: Keep containers sealed, use leak-proof and impact-resistant packaging
Compatibility During Transit: Segregate from food items, strong acids, oxidizers
Label Requirements: Mark as irritant, note environmental persistence concerns
Chemical Inventories: Listed on global registries for laboratory chemicals in some regions (such as TSCA in the US, REACH pre-registration in the EU)
Workplace Controls: Subject to general workplace safety rules for hazardous laboratory chemicals, including employee right-to-know standards
Environmental Restrictions: Avoid direct release to environment, report significant spills under regional guidelines
