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Looking Closer at 1-Chloro-2,2,2-Trifluoroethane: Its Path and Impact

Historical Development: A Shift in Chemistry and Industry

The journey of 1-chloro-2,2,2-trifluoroethane runs alongside society’s struggle with environmental and health challenges tied to industrial chemistry. Back in the 1930s, chemists built a whole family of chlorofluorocarbons, lauded for their low reactivity and thermal stability. By the late 20th century, the ozone hole snapped the world to attention, and regulatory tides turned against many CFCs. The industry pivoted, searching for alternatives that might balance the demands of cooling, cleaning, and safe handling, without the devastating atmospheric fallout. Among the compounds that took the stage, 1-chloro-2,2,2-trifluoroethane—often called HCFC-133a—offered a blend of performance and, at one time, a perceived lesser environmental punch. Its adoption rode this wave, even as new questions emerged about the long-term cost of so-called transitional chemicals.

Understanding the Compound: What 1-Chloro-2,2,2-Trifluoroethane Brings

1-Chloro-2,2,2-trifluoroethane holds a reputation for being a volatile colorless liquid, with a vapor that is heavier than air. Its chemical formula, C2H2ClF3, paints a picture of high electronegativity and a lack of easy flammability. I have seen it discussed in research circles as a solvent, refrigerant, or chemical intermediate where issues of ozone depletion and ease of transport matter. Its common names, such as HCFC-133a or R-133a, show up in technical and regulatory documents. Each bottle or cylinder often carries dense technical labeling, spelling out hazards, purity benchmarks, and UN transport numbers, reflecting the close attention regulators and handlers pay to these chemicals.

Physical and Chemical Properties: Risk and Use in the Balance

This compound boasts a boiling point near room temperature, around 7°C or so, and a density that makes leaks easy to spot on the cool floor of a lab or factory. Its solvent properties make it attractive in cleaning applications where less polar compounds might fail. The presence of both chlorine and fluorine atoms, combined with a relatively low carbon count, means 1-chloro-2,2,2-trifluoroethane spreads quickly, but breaks apart in the atmosphere over seasons rather than centuries. Its reactivity with strong acids, bases, and some metals does require respect—there’s no shortage of research outlining degradation pathways that generate harmful byproducts, requiring strict controls.

Preparation and the Chemistry Behind Synthesis

The production of HCFC-133a generally leans on halogen exchange reactions, which involve replacing hydrogen or non-fluorinated methyl groups with fluorine using strong fluorinating agents under heat and pressure. Patents and industrial literature describe routes starting with chlorotrifluoroethylene or related precursors. Scale-up means handling toxic intermediates and corrosive agents, pushing safety and technical teams to design dense, closed systems. The economic and technical barriers to entry for such chemicals keep production concentrated in a handful of facilities with the infrastructure to recycle reagents, limit emissions, and clean up hazardous waste.

Chemical Reactions and Making Modifications

Chemists see 1-chloro-2,2,2-trifluoroethane as both a target and a stepping stone. The electron-poor nature of its carbon-halogen bonds encourages nucleophilic replacements under the right conditions, while its resistance to simple hydrolysis and reduction speaks to the influence of so many fluorine atoms. Over the last decade, I’ve seen researchers tweak it for fluorination chemistry, turning it into other specialty compounds. This is less about large-volume manufacture and more about chasing particular properties—high performance in lubricants, unique characteristics in electronics, or improved selectivity in pharmaceuticals.

Getting the Label Right: Technical Specifications and Legal Detail

Strict regulations drive how this chemical gets labeled and traded. Each shipment meets defined purity standards to prevent dangerous cross-reactions or environmental mishaps—packing lists usually mention content, gross and net weight, and compliance marks from regulatory agencies. There’s an imperative to spell out hazard signals and transport rules since accidental releases have both human and environmental impacts. The US Environmental Protection Agency and similar bodies abroad mandate tracking, with the Montreal Protocol pushing countries to cut back on production and import of HCFCs. Manufacturers and users need to stay nimble to adapt to evolving limits and reporting demands.

Other Names in the Trade: Synonyms and Product Naming

Out in the world of commerce and regulations, 1-chloro-2,2,2-trifluoroethane travels under several flags: HCFC-133a, R-133a, and sometimes by its systematic name. I’ve come across all these in technical bulletins, environmental impact studies, and customs declarations. Knowing these aliases matters, as failing to connect the dots can mean missed compliance issues or wasted research.

Safety and the Realities of Using HCFC-133a

Safety comes front and center with chemicals like this. Direct exposure to vapor can irritate eyes and airways, particularly where ventilation fails or personal protective equipment falls short. Liquid spills threaten frostbite due to rapid vaporization, and confined spaces turn this gas into an asphyxiation risk. Handling protocols require site-specific training, leak-proof gear, and frequent checks using gas sensors. Guidelines don’t stop at worker safety; spill kits and containment routines keep emissions to a minimum, since even brief releases can cause wider harm in factories or neighborhoods. The history of chemical safety disasters builds a strong case for being prepared every time a drum gets moved or a valve cracks open.

The Range of Uses: How and Where 1-Chloro-2,2,2-Trifluoroethane Shows Up

Despite a shrinking window of legal use, HCFC-133a hung on longest as a refrigerant in legacy equipment, a cleaning agent in precision electronics, and an intermediate in specialty chemical manufacture. I remember seeing it called for in older chillers and test systems where designers banked on its properties long before current bans tightened their grip. In electronics, especially aerospace and defense, its non-flammability and cleaning power once gave it an edge where contaminants or static risks spelled disaster. Patent records and chemical catalogs from earlier decades list it as both a primary and secondary ingredient across industries, a testament to its versatility and ease of blending with other halocarbons.

The Research Race: Improving, Replacing, or Phasing Out

Research into HCFC-133a has piled up, covering every angle from physical chemistry to health and environmental science. Early work focused on making production safer and more cost-efficient, while more recent studies map out the atmospheric chemistry, breakdown products, and long-lived consequences. Academic groups and government labs zero in on alternatives with shorter atmospheric lifetimes, or zero ozone depletion potential. Current funding often steers away from extending HCFC lifespans and toward finding greener replacements—or tech that lets old systems retire safely. Policy and science interact here, with innovation driving change as much as regulation enforces it.

Toxicity and Exposure: Known Hazards and Lingering Worries

Health risks from 1-chloro-2,2,2-trifluoroethane grab headlines and inform workplace rules alike. Acute exposure runs from dizziness and respiratory impacts to heart sensitization in extreme cases. Chronic exposure studies, though rarer, hint at links with liver and kidney stress. Animal studies—often required by regulatory agencies—document tissue damage, reproductive effects, and subtle neurological changes at certain dosages. Data remains incomplete because many newer chemicals spend less time in use before facing replacement, but the accumulated experience with chlorofluorocarbons and halons leaves little doubt: routine exposure, especially in under-regulated settings, spells trouble over time. Fixing these problems means stricter controls, better education, and active monitoring of both workplace and community health.

The Road Ahead: Learning from the Rise and Fall of HCFCs

Innovation and regulation shape the future for compounds like 1-chloro-2,2,2-trifluoroethane. As international agreements tighten the screws on any chemical tied to ozone holes or climate risk, manufacturers push to retire old recipes and launch new designs that trade performance for safety. My work in this field tracks conversations that have moved from patching over risks to genuine replacement. Products coming into focus either break down fast in the environment or rely on entirely new chemistries, developed with sustainability as the first principle, not an afterthought. The story of this and related compounds shouldn’t fade into nostalgia. Instead, it stands as a lesson written in patents, plant records, and public health surveys: progress comes not just from invention, but from stepping up when science and society demand better answers.




What is 1-Chloro-2,2,2-Trifluoroethane used for?

From the Lab to Industry

Stepping into any chemical plant or electronics facility, you might not hear much talk about 1-Chloro-2,2,2-Trifluoroethane by name. Usually, it goes by a code, HCFC-133a, or gets lumped in with other refrigerants. Still, this colorless gas stands out in more jobs than most folks realize. For decades, it filled canisters for cleaning, cooled things down in tight spots, and played a part in whipping up other useful products.

Chasing Cleanliness in Electronics

Growing up with geeky hobbies, I learned early that cleaning sensitive electronics needs something that pulls dirt out, dries fast, and doesn’t fry the board. People in the field kept turning to fluorinated solvents like 1-Chloro-2,2,2-Trifluoroethane. With all the tiny traces on circuit boards, nothing short of magic seems to pull them off safely—except a select group of chemicals. This one dries fast, leaves little behind, and won’t ignite at the first spark. That makes it helpful for washing everything from phone chips to aerospace equipment.

Its Role in Refrigeration

Cracking open an old air conditioning unit, you learn about the inner lives of refrigerants. HCFC-133a took to this role because it doesn’t break down so easily and keeps temperatures steady. Unlike the old villains in the neighborhood, like CFCs, this one does less damage to the ozone layer. The shift started as more regulations squeezed out the worst offenders, so industries latched onto molecules like this one while searching for greener answers.

The Manufacturing Middleman

Beyond just moving heat or cleaning circuit boards, this chemical acts as a stepping stone. Chemists rely on it to make more advanced substances, including some pharmaceuticals and polymer goods. In these spots, a predictable reaction means less waste, better safety, and tight quality control. Its stability means fewer surprises in the process—something both scientists and CEOs can appreciate.

Big Questions About Safety and the Environment

The story here isn’t only about usefulness. Any solvent that evaporates into the air or goes down a drain brings heavy baggage. Scientists flagged 1-Chloro-2,2,2-Trifluoroethane as less threatening to the ozone than some old substances, though it still lingers in the atmosphere for years. Studies show it can add to global warming if released in large amounts. So while manufacturers adopted it as a ‘better’ choice, the long-term game pushes the world to drop hydrofluorocarbons in favor of less worrisome chemicals run by newer tech.

A Push for Safer Solutions

Bans and phase-outs push companies to hunt for smarter replacements. In my work with local repair shops and labs, every technician knows that the days of easy solvents are gone. Water-based cleaners, safer blends, and advanced refrigerants keep popping up, even if they cost more or come with a learning curve. Industry leaders, especially in Europe and North America, pull harder for accountability, demanding traceability and audits to make sure practices match the promises made on paper.

Looking Forward

While 1-Chloro-2,2,2-Trifluoroethane helped bridge the world toward less harmful chemicals, it feels more like a stepping stone than a permanent fix. The march toward cleaner industry takes creativity, regulation, and a willingness to spend money on tomorrow’s answers rather than yesterday’s habits. Every year brings news about safer solvents, cleaner processes, and tighter laws—none of which work without buy-in from users and managers alike. It all starts by actually learning what’s in the can and where it heads once it leaves the bottle.

What are the safety precautions when handling 1-Chloro-2,2,2-Trifluoroethane?

Understanding Real Risks

Working with any chemical demands respect, but 1-Chloro-2,2,2-Trifluoroethane (often called HCFC-133a) brings unique hazards. As someone who has spent time in industrial settings, I have seen what happens when folks let their guard down around refrigerants. This compound may seem tame compared to some acids or solvents, but the wrong step exposes you to serious health issues.

Inhalation brings immediate, sometimes invisible danger. This refrigerant pushes out oxygen in closed spaces, leading to lightheadedness, confusion, or worse. I remember once, on a factory floor, watching a colleague stagger out of a poorly ventilated room—his face gray, his breathing shallow. He recovered, but the scare stuck with the team for weeks. Proper ventilation needs more than just an open door. Install real exhaust systems and use portable detectors for both gas leaks and oxygen levels, because you can’t taste or smell this stuff before it gets risky.

Skin and Eye Hazards Aren’t Small Fries

Liquid or high-concentration vapor from HCFC-133a chills skin on contact. That means frostbite. During transfers or spills, splashes can freeze flesh or leave deep burns. I keep chemical-resistant gloves, goggles, and long sleeves handy—not because the label says so, but because I’ve seen what happens to skin left unprotected. One rushed transfer can send you to the ER with numb fingers and blisters. Never forget how quickly things go wrong if you swap goggles for regular glasses or grab porous gloves from the shelf.

Fire and Chemical Stability

Flammability doesn’t shout for attention with 1-Chloro-2,2,2-Trifluoroethane, but that turns into a trap. The gas itself won’t catch fire easily, yet when heated above certain temperatures, the fumes break down and release nasty byproducts like hydrogen chloride and phosgene. Both can damage lungs for life. Avoid open flames, hot work, or even sunlight near storage or decanting stations. Connect detectors and alarms around storage spots—complacency in this area ruined more than one batch and landed workers in the hospital.

Smart Storage and Handling

Store these cylinders upright in cool, dry spots, away from direct heat or mechanical impact. Mark them with clear hazard labels—no scribbles or half-peeled stickers. Mishaps with stored HCFC-133a aren’t just fire stories. High pressure builds up inside the containers, and rough handling can send cylinders rocketing across storage rooms. Straps, chocks, and cage systems help, and every worker should see the right way to move and secure these tanks, not just the senior techs.

Regular inspections catch leaks early. Look for frost rings around valves or hissing from connections. Use leak detection fluid or electronic sniffers. Relying on smell fails with 1-Chloro-2,2,2-Trifluoroethane—it’s practically odorless.

Training and Emergency Prep

Everyone on shift needs real training, not just handouts or signatures on a form. Drills and short, direct talks on what to do in a spill, how to use eye-wash stations, and where to run in a leak situation can save lives. I’ve seen rushed workers skip the basics and pay dearly. Keep emergency contacts at eye level, and always know the route to fresh air or a safe refuge. Make PPE a habit, not an afterthought.

1-Chloro-2,2,2-Trifluoroethane rewards respect and steady habits. Protecting yourself starts with simple steps and a refusal to let routine dull your caution. Stay alert, use the right gear, and never handle this chemical alone in closed rooms.

What is the chemical formula of 1-Chloro-2,2,2-Trifluoroethane?

A Closer Look at the Formula

1-Chloro-2,2,2-trifluoroethane doesn’t exactly roll off the tongue, and its structure tells an interesting story about progress in chemistry. Its formula—C2H2ClF3—hints at a larger conversation around safety, environmental science, and the direction technology has taken in the past few decades.

The Human Side of the Periodic Table

Every bottle and cylinder tucked away in supply rooms or laboratories is more than a code or formula; behind these labels, choices are made that have ripple effects on everything from technician health to the climate. Plenty of folks in industrial and research labs remember the old days of less regulated refrigerants and cleaning chemicals. I’ve spent time wrestling open jammed valves on old cylinders that once held compounds like 1-chloro-2,2,2-trifluoroethane. Every time, those long names underline that we’re dealing with molecules designed to perform specific jobs — and not all jobs carry the same risk or reward.

Why the Formula Matters

C2H2ClF3 isn’t just static information. It signals the presence of carbon (C), hydrogen (H), chlorine (Cl), and fluorine (F). Fluorine and chlorine, in particular, have played a big role in shaping how we measure environmental risk. Folks remember the phaseout of old refrigerants—think CFCs and HCFCs—because of ozone damage, and many of us have watched with frustration as banned chemicals stick around decades after being flagged as harmful.

People sometimes glaze over at formulas, but that combination of elements can help explain why a substance behaves as it does. Fluorine, incredibly reactive and stubbornly persistent, improves certain properties but leads to environmental headaches by resisting breakdown. Chlorine often adds to the toxicity profile. The inclusion of both in a compact molecule means careful handling for technicians. Seeing these elements together never feels routine. I’ve worn gloves, masks, and prayed no seal would crack, knowing inhalation or contact could mean a trip to the emergency room.

Lessons From Regulation

It wasn’t all that long ago the industry leaned hard on hydrochlorofluorocarbons for fridges and cleaning solvents. C2H2ClF3 belongs to that group. The formula sits in regulatory crosshairs because compounds like it have an ozone depletion potential and a high global warming potential. Scientists, backed by plenty of data, pushed for new rules. Challenge is, every phaseout takes planning and costs money. My generation saw whole product lines redone and new training for handling replacement chemicals.

The lesson? Chemical formulas aren’t only for textbooks. They shape policy, affect the air we breathe, and the kinds of risks workers take on the job. Knowing the formula gave regulators, inventors, and end users more control in weighing risk versus utility.

The Way Forward

There’s been progress. Modern refrigerants use alternate elements and structures, guided by solid research, to lower environmental impacts. Transparency around what’s inside each cylinder or can has improved, too. Engineers, chemists, and plant managers have benefited from that clearer information—less guesswork, fewer mishaps, and, with luck, cleaner air. Knowing what C2H2ClF3 represents lets professionals make smarter choices, from replacement strategies to emergency response.

Every time I encounter a chemical formula at work, it feels less like a puzzle and more like a roadmap. Understanding it gives the industry a chance to build safer, smarter technologies—without repeating past mistakes.

How should 1-Chloro-2,2,2-Trifluoroethane be stored?

Why Proper Storage Counts

People often overlook how chemicals shape our day-to-day lives. Growing up around farms and workshops, I learned early that mishandling solvents and refrigerants doesn’t just risk property—it risks lives. 1-Chloro-2,2,2-trifluoroethane (also known as HCFC-133a) sits on the list of chemicals that demand care, not just because of potential environmental impact, but because sloppy storage creates fire and health hazards right at home, on the job, in a warehouse, or even at a research lab.

Understanding the Real Risks

Getting facts straight changes perspectives. 1-Chloro-2,2,2-trifluoroethane boils at just above room temperature and puts off vapors that can displace oxygen, knock someone unconscious, or damage heart rhythm if inhaled at high concentrations. Leaky storage leads to rapid evaporation. In a confined or poorly ventilated space, that means real danger.

Fluorinated hydrocarbons ignite under specific conditions. Sparks aren’t welcome in a storeroom with loose vapor. Overheating tanks or cylinders ramps up pressure and can rupture container walls, shooting shrapnel—something I’ve actually seen during a training session on industrial safety.

Simple Ground Rules for Storage

Safe storage doesn’t call for plenty of guesswork, just clear steps backed by research. The Centers for Disease Control and Prevention (CDC), along with industrial safety standards, set the basic framework.

  • Keep containers upright, sealed, and labeled: Open containers lose more than product—they threaten people in the building. Use original packaging or pressure-rated tanks, and label everything in plain language.
  • Choose a cool, dry, and well-ventilated area: Sunlight or hot machinery ramps up storage pressure. From years in warehouse work, I’ve seen equipment fail just from sitting too close to a steam pipe or heat vent. Open doors and exhaust fans matter.
  • Avoid ignition sources: No open flames, hot tools, switches, or even charged cell phones nearby. Talking to old-timers in the field, fire doesn’t even get a chance if containers stay clear of ignition.
  • Segregate from incompatible chemicals: Strong bases, acids, and oxidizers stand out as troublemakers. Keeping unrelated chemicals together just asks for a reaction. Stories circulate about entire storerooms lost from mixing chemicals that should never meet.
  • Spill kits and training nearby: In places I’ve worked, the only real difference between a close call and a major incident came down to who was ready with absorbent pads, personal protective equipment, and a good exit route.

Regulatory and Environmental Upsides

Global treaties like the Montreal Protocol set strict limits on releasing hydrochlorofluorocarbons. It isn’t just a matter of ticking regulatory boxes. Leaks from poor storage contribute to ozone depletion and climate shifts. Proper handling cuts emissions that affect air quality for years to come.

Getting rid of old or empty containers takes a certified process. Local hazardous waste facilities handle the job much better than a landfill. Proper documentation shields individuals and companies from legal trouble—a lesson emphasized in every chemical safety seminar I’ve attended.

Better Practices for a Safer Future

The attitude around chemical storage shifts with better information. Responsible companies push for regular inspections, updated spill response plans, and designated safety leaders. Automation technology spots leaks and monitors room temperature. Training new team members always ranks higher than assuming “someone else is taking care of it.”

Safe storage of 1-Chloro-2,2,2-trifluoroethane means more than just a quick fix. It secures health, property, and reputation. A bit of common sense grows from experience—and a bit of reading up on the facts keeps risks low.

Is 1-Chloro-2,2,2-Trifluoroethane harmful to the environment?

Everyday Chemistry Finds Its Way Outdoors

A lot of household goods and industrial fluids rely on fluorinated chemicals. 1-Chloro-2,2,2-Trifluoroethane, also known as HCFC-133a, comes from the same family as a lot of the coolants and solvents used in the past few decades. When people talk about harm to the environment, most bring up CFCs and their impact on the ozone layer. HCFCs like this one are often marketed as replacements — but the story doesn’t end there.

Breaking Down Its Impact

Everyone who follows environmental news knows the phrase “ozone depletion.” The world agreed to phase out the worst offenders through the Montreal Protocol in the late 1980s. HCFCs like 1-Chloro-2,2,2-Trifluoroethane didn't get banned straight away. They break down faster in the atmosphere, so they don’t last as long as older CFCs. That made them look like a safer bet.

Still, compared to simple carbon dioxide, these chemicals pack a serious punch. 1-Chloro-2,2,2-Trifluoroethane may not last as long high up, but while it’s around, it has more power to trap heat — its global warming potential is over a thousand times higher than CO₂ over a 100-year period. Toss enough of it into the air, and it starts to add up. Every bit released matters.

Real-World Evidence: Small Amounts, Big Worries

Studies from atmospheric monitoring stations show traces of HCFC-133a all over the planet, even in places far from factories. Researchers from NASA and other organizations found steady increases in the air, year after year, even though no one produces it intentionally anymore in most countries. Industries may leak it as a byproduct or during maintenance. In my city, old refrigerators and air conditioners sometimes still choke out gases like this, despite rules that try to limit releases.

It’s not just about numbers in a chemical database or some faraway glacier ice core. In past volunteer clean-ups at local recycling centers, workers often had little training for handling chemical coolants. If cans or machinery get scrapped without safe recovery, these gases escape. Few realize every hiss from a leaky valve can stick around the atmosphere long enough to matter.

Looking at Solutions

The good news: international treaties set hard deadlines for phasing out HCFCs, and that even helped slow ozone layer damage. Many countries keep strict controls on imports and exports. In my own work, local businesses turn to reclaimed or recycled refrigerants and new blends based on hydrofluoroolefins (HFOs), which tend to break down faster into simple molecules. When people repair their old fridges or air conditioners, asking about refrigerant recovery isn’t just savvy — it’s a way to protect the air for everyone.

Education plays a big role. DIY mechanics can find low-cost “recovery bags” at automotive stores now. Cities offer chemical collection days. It’s easier to make the right choice if local programs stay well funded and consumers know what’s in their basements and garages.

Why It Matters

Every chemical has a legacy. Chemicals like 1-Chloro-2,2,2-Trifluoroethane linger long after their original use. Anyone who helps keep these substances out of the sky or switches to safer options chips away at the bigger problem. Paying attention to what goes in the air above us means leaving behind a safer world, not just for the next town over, but for the kids growing up today.

1-Chloro-2,2,2-Trifluoroethane
1-Chloro-2,2,2-Trifluoroethane
1-Chloro-2,2,2-Trifluoroethane
Names
Preferred IUPAC name 1-chloro-1,1,1-trifluoroethane
Other names HCFC-133a
R-133a
Halogenated hydrocarbon 133a
CF3CH2Cl
Ethane, 1-chloro-2,2,2-trifluoro-
Pronunciation /ˈklaɪrəʊ tuː tuː tuː ˈtrɪfluərəʊˌɛθeɪn/
Identifiers
CAS Number 75-88-7
Beilstein Reference 1200920
ChEBI CHEBI:40435
ChEMBL CHEMBL2106887
ChemSpider 20813
DrugBank DB13424
ECHA InfoCard ECHA InfoCard: 100.005.676
EC Number 200-872-4
Gmelin Reference 4725
KEGG C19128
MeSH D002965
PubChem CID 6383
RTECS number KH8225000
UNII YB94279J05
UN number UN1022
Properties
Chemical formula C2H2ClF3
Molar mass 102.48 g/mol
Appearance Colorless liquefied gas
Odor Ethereal odor
Density 1.352 g/mL at 25 °C
Solubility in water 0.11 g/100 mL (20 °C)
log P 0.92
Vapor pressure 154.18 hPa (20 °C)
Acidity (pKa) 15.8
Basicity (pKb) Basicity (pKb): 16.05
Magnetic susceptibility (χ) -0.71e-6 cm³/mol
Refractive index (nD) nD 1.284
Viscosity 0.406 cP (25°C)
Dipole moment 2.41 D
Thermochemistry
Std molar entropy (S⦵298) 316.1 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -586.5 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -1050.4 kJ/mol
Pharmacology
ATC code N01AB09
Hazards
Main hazards Harmful if inhaled. Causes skin and eye irritation. May cause drowsiness or dizziness.
GHS labelling GHS02, GHS04
Pictograms GHS04,GHS07
Signal word Warning
Hazard statements H220, H280, H319
Precautionary statements P210, P261, P271, P304+P340, P403
NFPA 704 (fire diamond) 1-1-0
Autoignition temperature 728 °C
Explosive limits Explosive limits: 8.5–16.9%
Lethal dose or concentration Lethal Concentration (LC50, inhalation, rat): 291000 ppm (4 hours)
LD50 (median dose) LD50 (median dose): Oral rat 1500 mg/kg
NIOSH KL6500000
PEL (Permissible) PEL (Permissible Exposure Limit) of 1-Chloro-2,2,2-Trifluoroethane is 1000 ppm (TWA).
REL (Recommended) 50 ppm (8-hour TWA)
IDLH (Immediate danger) IDLH: 1,000 ppm
Related compounds
Related compounds Chlorodifluoromethane
Dichlorofluoromethane
Trichlorofluoromethane
1,1,1-Trichloroethane
1,1,1,2-Tetrafluoroethane