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Product Name: 1,3-Dichloroacetone
Chemical Formula: C3H4Cl2O
CAS Number: 534-07-6
Synonyms: 1,3-Dichloro-2-propanone; Dichloroacetone
Recommended Use: Intermediate in organic synthesis
Manufacturer’s Details: Contact information listed in supplied documentation
Emergency Contact Number: Refer to local emergency service
Classification: Acute Toxicity – Oral (Category 3), Skin Corrosion/Irritation (Category 2), Eye Damage (Category 1), Specific Target Organ Toxicity (Single Exposure – Category 3)
Warning: Danger
Hazard Statements: Toxic if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Pictograms: Skull and crossbones, exclamation mark, corrosion
Precautionary Statements: Do not breathe dust, fume, gas, mist, vapors, spray. Wash hands thoroughly after handling. Wear protective gloves/protective clothing/eye protection/face protection.
Chemical Name: 1,3-Dichloroacetone
Concentration: 100%
Impurities/Additives: None known affecting classification
Molecular Weight: 126.97 g/mol
Inhalation: Move person to fresh air immediately. If breathing is difficult, seek medical attention without delay. Provide oxygen if available.
Skin Contact: Remove contaminated clothing. Rinse skin with generous quantities of water for at least 15 minutes. Seek medical attention for persistent irritation.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and continue rinsing. Get medical attention immediately.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek immediate medical attention.
Most Important Symptoms: Burning sensation, headache, dizziness, shortness of breath, digestive discomfort, skin redness, eye damage.
Notes to Physician: Treat symptomatically. Monitor for respiratory distress and irritation-related complications.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide.
Unsuitable Extinguishing Media: Avoid high-pressure water streams as spread contamination.
Specific Hazards Developing from Substance: Releases toxic vapors (hydrogen chloride, phosgene, carbon monoxide) under fire conditions.
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear. Avoid inhalation of combustion products.
Thermal Decomposition Products: Hydrogen chloride, carbon oxides, phosgene.
Personal Precautions: Ventilate area. Avoid contact with skin, eyes. Do not breathe vapors. Wear gloves, protective goggles, chemical apron, and suitable respirator.
Environmental Precautions: Prevent further leakage or spillage. Do not allow entry into drains, watercourses, or soil.
Containment and Cleanup Methods: Absorb with inert material (sand or earth). Use spark-proof tools. Sweep up and shovel into suitable containers for disposal. Clean surface with water and detergent.
Additional Instructions: Remove all ignition sources. Isolate area.
Safe Handling Measures: Use in a well-ventilated area or chemical fume hood. Avoid inhalation and contact with skin or eyes. Keep away from open flames, spark-producing equipment, and sources of ignition.
Storage Recommendations: Store in tightly sealed original container, in a cool, dry, well-ventilated area. Segregate from strong acids, bases, oxidizers.
Specific Requirements: Use explosion-proof electrical, ventilating, lighting equipment. Ground and bond container and receiving equipment.
Incompatibles: Strong alkalis, reducing agents, strong acids, metals.
Exposure Limits: No specific national or international occupational exposure limits established.
Engineering Controls: Chemical fume hood, safety shower, eyewash station. Use local exhaust ventilation.
Personal Protection: Chemical-resistant gloves, protective goggles, face shield, protective clothing, respiratory protection as appropriate.
Hygiene Measures: Wash hands and exposed skin thoroughly after handling. Do not eat, drink, or smoke while using the product.
Appearance: Colorless to pale yellow liquid
Odor: Pungent, sharp
pH: Not applicable
Melting Point: ~ -5 °C
Boiling Point: ~ 145 °C
Flash Point: 52 °C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid and vapor
Vapor Pressure: 3 mmHg at 20 °C
Relative Density: 1.38 g/cm³ at 20 °C
Water Solubility: Moderately soluble
Partition coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not available
Decomposition Temperature: Not available
Viscosity: Not determined
Chemical Stability: Stable under recommended conditions, avoiding sources of ignition and incompatible materials.
Reactivity: May react vigorously with strong bases and acids, generating heat and toxic gases.
Hazardous Reactions: Formation of hazardous decomposition products possible with incompatibles.
Incompatible Materials: Strong alkalis, strong acids, oxidizing agents, active metals.
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, phosgene, chlorine gas.
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion.
Acute Toxicity: LD50 (oral, rat): 118 mg/kg; toxic by ingestion and inhalation.
Skin Corrosion/Irritation: Causes severe skin burns and irritation.
Serious Eye Damage/Irritation: Causes serious eye damage, risk of blindness.
Respiratory Sensitization: Respiratory tract irritation, cough, headache, dizziness, possible respiratory depression.
Chronic Effects: Prolonged or repeated exposure may cause dermatitis, organ damage not well documented.
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA as of latest data.
Mutagenicity/Teratogenicity: Data deficient; use precaution.
Ecotoxicity: Harmful to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Expected to have moderate persistence, partial biodegradability; specific data limited.
Bioaccumulative Potential: Information not fully available; low to moderate potential expected.
Mobility in Soil: Likely mobile due to water solubility; may contaminate groundwater.
Other Adverse Effects: Releases toxic compounds; avoid uncontrolled environmental release.
Disposal Methods: Dispose of contents/container in accordance with local, regional, national, international regulations. Use licensed chemical waste contractor.
Contaminated Packaging: Empty containers retain residue; handle as hazardous waste.
Special Precautions: Do not allow to reach sewage system, surface or ground water. Consider incineration in chemical incinerator equipped with afterburner and scrubber.
UN Number: UN 3265
Proper Shipping Name: Corrosive Liquid, Acidic, Organic, N.O.S. (contains 1,3-Dichloroacetone)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Environmental Hazards: Yes
Special Precautions for User: Use original container, keep upright, segregate from incompatible materials. Emergency procedures for spills.
Transport in Bulk: Not advised without specific regulatory compliance.
Safety, Health, and Environmental Regulations: Listed or regulated under chemical safety laws in most jurisdictions. Subject to OSHA (Occupational Safety and Health Administration) hazardous chemical standards. Included under EPA (Environmental Protection Agency) TSCA (Toxic Substances Control Act) inventory.
Hazard Communication: Requires label and Safety Data Sheet under GHS, CLP, and OSHA HCS rules.
Chemical Inventory: Listed on EU REACH, US TSCA, and other major chemical inventories.
Additional Regulations: May be classified as a dangerous good under ADR, IMDG, DOT.
