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Material Safety Data Sheet for 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoglycerol Sodium Salt

Identification

Product Name: 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoglycerol Sodium Salt
Synonyms: DPPG-Na, Sodium 1,2-dipalmitoylphosphatidylglycerol
CAS Number: 200880-41-7
Recommended Use: Research, biochemical studies, pharmaceutical formulations
Restrictions on Use: Not for human or animal ingestion, not for food or cosmetic applications
Supplier: Named distributor or laboratory supply company
Emergency Telephone Number: Provided by local or site-specific emergency services

Hazard Identification

GHS Classification: Not classified as hazardous according to GHS criteria
Physical Hazards: No particular reactivity with water, does not present significant fire risk under expected conditions
Health Hazards: Inhalation of dust may irritate respiratory tract; contact with eyes may cause slight irritation; skin exposure may produce mild discomfort for sensitive individuals
Environmental Hazards: Limited data on aquatic toxicity; material not expected to persist or bioaccumulate
Hazard Statements: May cause mechanical irritation to eyes and respiratory tract from fine particulate under conditions of improper handling
Precautionary Statements: Avoid inhalation of dust, use personal protection, practice good laboratory hygiene

Composition / Information on Ingredients

Chemical Name: 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoglycerol Sodium Salt
Component: Pure phospholipid compound
Concentration: >99% by weight
Notable Impurities: No known hazardous impurities present in typical laboratory grades
Molecular Formula: C38H74NaO10P
Molecular Weight: 776.95 g/mol

First Aid Measures

Inhalation: Move affected person to fresh air. Seek medical attention if symptoms such as coughing, irritation, or shortness of breath persist.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and plenty of water; seek medical attention if any irritation develops or does not resolve.
Eye Contact: Immediately rinse eyes with plenty of water for at least 15 minutes, holding eyelids open. If irritation, redness, or visual disturbances occur, consult a physician.
Ingestion: Rinse mouth with water. Do not induce vomiting except by medical instruction. Seek prompt medical attention if significant amounts are swallowed or if symptoms appear.
Important Symptoms: Mild irritation to mucous membranes (rare), persistent redness, coughing

Fire-Fighting Measures

Suitable Extinguishing Media: Use foam, carbon dioxide, dry chemical powder, or water spray
Unsuitable Extinguishing Media: Direct streams of water can spread spilled powder, making cleanup difficult
Specific Hazards: Thermal decomposition in fire may release carbon oxides, sodium compounds, and phosphorus oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full turnout gear to prevent inhalation of combustion products
Special Precautions: Cool exposed containers with spray to prevent rupture, contain run-off to prevent uncontrolled environmental contamination

Accidental Release Measures

Personal Precautions: Avoid generating dust; wear appropriate personal protective equipment (gloves, safety glasses, lab coat, dust mask)
Environmental Precautions: Prevent product from entering drains, waterways, or soil to limit environmental contamination
Cleanup Methods: Collect spill with an inert, non-combustible material such as sand or vermiculite. Gather in labeled containers for disposal.
Decontamination: Wash spill area with water and mild detergent to minimize slip hazard and remove residues

Handling and Storage

Handling: Use in well-ventilated areas; minimize dust generation. Avoid contact with skin and eyes by wearing standard lab gloves and goggles. Clean up spills quickly to prevent slip hazards.
Storage: Store in tightly closed bottles or vials, away from heat, light, and strong oxidizers. Maintain storage at recommended temperatures according to the manufacturer—typically -20°C for best stability.
Hygiene Practices: Wash hands thoroughly after handling, especially before eating or drinking. Do not return unused material to the original bottle if contaminated.
Incompatibilities: Strong oxidizers, bases, or acids can degrade phospholipids and should be kept away from storage areas

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this compound under OSHA, ACGIH, or NIOSH
Engineering Controls: Operate in a chemical fume hood or controlled laboratory environment
Personal Protection: Wear chemical-resistant gloves (nitrile or latex), safety goggles, and lab coat to avoid contact. Use a dust mask or particulate filter if the material is handled as a dried powder and risk of inhalation exists.
Environmental Controls: Use spill containment measures to prevent unintended release

Physical and Chemical Properties

Appearance: White to off-white powder or crystalline solid
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): Neutral to slightly alkaline
Melting Point/Freezing Point: Approx. 65–67°C
Boiling Point/Range: Not determined (decomposes)
Flash Point: Not flammable
Evaporation Rate: Not volatile
Flammability: Non-flammable
Explosive Properties: No explosive properties
Vapor Pressure: Negligible at room temperature
Vapor Density: Not relevant
Relative Density: ~1.1-1.2 g/cm³
Solubility: Soluble in water and some organic solvents
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not relevant

Stability and Reactivity

Chemical Stability: Chemically stable under recommended storage and handling conditions
Reactivity: Non-reactive under normal laboratory conditions. Susceptible to hydrolysis or oxidation if heated strongly or exposed to acidic or basic conditions
Hazardous Reactions: No dangerous polymerization or decomposition reactions expected
Conditions to Avoid: High temperatures, exposure to light or moisture, contact with incompatible chemicals like oxidizers and acids
Incompatible Materials: Strong oxidizers, acids, alkalis
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phosphorus oxides, sodium oxides under fire or extreme heat

Toxicological Information

Acute Toxicity: No data available for oral, dermal, or inhalation toxicity in humans or animals; low acute toxicity expected based on structure and class
Skin Corrosion/Irritation: Generally not considered a skin irritant; possible mild irritation on sensitive skin or with prolonged contact
Eye Damage/Irritation: Dust can mechanically irritate eyes causing mild redness or discomfort
Respiratory or Skin Sensitization: No reports of allergic reactions or sensitization in literature
Chronic Effects: No chronic toxicity reported; no known target organ effects
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not listed by IARC, NTP, or OSHA as carcinogenic, mutagenic, or teratogenic; not expected to pose such risks
Other Effects: Typical laboratory precautions and safe handling reduce risk of adverse health effects

Ecological Information

Toxicity to Aquatic Life: No specific test data, but phospholipidic substances usually show low toxicity to aquatic organisms
Persistence and Degradability: Readily biodegradable; phospholipids degrade into natural substances
Bioaccumulative Potential: Not expected to bioaccumulate due to breakdown in environment and low solubility in lipid-rich tissues
Mobility in Soil: Low mobility; binds to soil particles and organic matter
Other Adverse Effects: Does not contain heavy metals, persistent organic pollutants, or toxic impurities

Disposal Considerations

Disposal Methods: Dispose of residue and contaminated materials as laboratory solid waste, following institutional and local environmental regulations
Contaminated Packaging: Triple rinse, then dispose with appropriate chemical waste
Precautions: Do not discharge to natural waters, soil, or drains; use licensed chemical waste disposal contractors for large quantities

Transport Information

UN Number: Not regulated for transport under ADR, IMDG, IATA
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: None assigned
Packing Group: None applies
Special Precautions: Avoid sources of contamination and mechanical damage during transport; keep container tightly closed, dry and cool

Regulatory Information

Inventory Status: Not specifically listed by national chemical inventories such as TSCA (US), REACH (EU), DSL (Canada)
Regulations: Laboratory use only; not classified as hazardous under OSHA, CLP, or GHS criteria
Other Requirements: Ensure proper labeling, safety instruction and training for personnel handling the compound
Workplace Controls: Follow institutional chemical hygiene policies and maintain safety data on site for accessibility and compliance