Name: 1,2-Dibromo-3-Butanone
Chemical Formula: C4H6Br2O
Appearance: Pale to light yellow liquid, pungent odor
Uses: Intermediate for organic synthesis, sometimes encountered in academic or industrial research
CAS Number: 34456-01-6
Common Synonyms: Dibromobutanone
Having personally worked in labs, I know how critical it is to keep information clear. Confusing chemical names can end up causing real accidents, so I appreciate it when labels stick to the point without company fluff.
Hazard Classification: Skin and eye irritant, toxic if ingested or inhaled, may cause respiratory tract irritation
Label Elements: Skull and crossbones for acute toxicity, exclamation mark for irritation
Potential Health Effects: Direct contact brings burning sensation, tearing, nausea, coughing or chest tightness
Environmental Hazards: Large spills threaten fish and aquatic life through bromine release
Anyone who's splashed a halogenated ketone on themselves understands why these warnings matter. Just knowing something stings or burns isn’t enough—real lives depend on detailed warnings, not just icons on a sheet.
Chemical Identity: 1,2-Dibromo-3-Butanone
Concentration: Typically 95-100 percent in research settings
Impurities: Possible traces of lighter dibrominated or chlorinated byproducts
People working with chemicals want to know exactly what's inside, not just glossy names. I once saw a so-called “pure” batch throw off unexpected reactions because the SDS left out trace contaminants.
Inhalation: Move to fresh air, keep at rest, seek medical assistance if symptoms persist
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse immediately under running water for at least 15 minutes, lift eyelids, consult eye specialist
Ingestion: Rinse mouth, do not induce vomiting, contact poison center or doctor
It’s not enough to say “rinse thoroughly”—clarity saves time under pressure. In my experience, even seasoned chemists freeze up in an emergency, which makes straightforward, actionable guidance absolutely vital.
Suitable Extinguishing Media: Use foam, CO2, dry chemical; water spray only to cool containers
Specific Hazards: May release HBr, bromine, carbon monoxide—noxious gases that demand ventilation
Special Protective Equipment: Firefighters should use self-contained breathing apparatus and chemical resistant gear
Firefighting Tactics: Approach from upwind direction, contain runoff, notify environmental agencies if water used
Having been in a building where chemical stores went up, I won’t forget how quickly brominated fumes spread. It's these ugly surprises—the smells, the speed, the hidden hazards—that go missing in basic fact sheets.
Personal Precautions: Wear gloves, goggles, lab coat; ventilate area
Environmental Precautions: Prevent spillage from reaching drains or soil
Containment: Cover spill with inert material like sand; scoop up, seal in labeled drums
Cleanup: Dispose as hazardous chemical waste, wash area with copious water
Many spills start with a splash nobody notices, and before long the damage stacks up. I’ve seen good intentions backfire, as people try to mop up with paper towels or flush toxic stuff down drains, failing to grasp what “toxic” really means for a neighborhood.
Handling: Avoid breathing vapors, use in chemical fume hood, secure containers tightly
Storage: Keep locked up in cool, dry, well-ventilated space away from heat, sunlight or acids
Incompatibilities: Strong oxidizers, acids, bases—all spell trouble for even careful chemists
It’s easy to underestimate how one overlooked leaky cap or a misplaced bottle can trigger disaster. Over years in shared labs, I learned to double-check others' storage, because chemical accidents don’t care about seniority.
Engineering Controls: Use chemical fume hoods, eyewash stations, and emergency showers
Personal Protective Equipment: Splash-proof goggles, chemical-resistant gloves, lab coat, sometimes a respirator
Hygiene Measures: Don’t eat, drink, or smoke near this compound; change out of contaminated gear promptly
Many students see PPE as optional until the day a spill lands on skin. The real world works differently from safety training videos, and it takes constant reminders—not boring platitudes—to keep people careful.
Molecular Weight: 229.90 g/mol
Boiling Point: Decomposes before boiling
Melting Point: Data scarce; liquid form at room temperature
Density: Approx. 2.1 g/cm³
Solubility: Limited in water, soluble in organic solvents
Odor: Strong, irritating
Physical properties might seem like trivia but shape every accident—think of how quickly vapors fill a space or whether a substance will simply evaporate. I take these numbers seriously because they dictate how fast you act.
Chemical Stability: Tends to be stable under normal temperatures and conditions, but breaks down with strong acids or bases
Conditions to Avoid: Heat, sunlight, incompatible chemicals
Hazardous Reactions: Vigorous decomposition with oxidizers, forms toxic gases including bromine, HBr, CO
Even after decades, stories still circulate about someone “just topping off” a flask and triggering disaster. The line between routine and disaster thins with unstable chemicals—the chemistry never reads the SDS.
Acute Toxicity: Can cause difficulty breathing, nausea, headaches, convulsions at higher exposures
Routes of Exposure: Inhalation, ingestion, skin, eye contact
Sensitization: No human data but irritation is well-documented
Chronic Effects: Possible liver or kidney effects with repeated overexposure—data on chronic exposure remains incomplete
Nothing frustrates me more than ambiguity in toxicity data. Researchers and students both deserve full transparency, even if it means publishing “we don’t know” instead of leaving people hanging.
Aquatic Toxicity: Known to be harmful or fatal to fish at low concentrations, especially because of bromine release
Persistence and Degradability: Tends not to break down quickly, builds up in soil or sediment
Bioaccumulation: Unclear, but brominated organics usually stick around
Disposing of halogenated waste in the wrong place can poison water for years. In environmental work, I saw neglected runoff come back as fish die-offs months later, and regret is no substitute for prevention.
Method: Collect residues and empty containers for handling as hazardous waste; do not put down drains
Recommended Practice: Send to licensed chemical disposal provider, incinerate with proper scrubbing
Precautions: Never reuse empty containers, label clearly, keep records
Disposal isn’t a chore for “someone else”—it’s my obligation as much as anyone's. Those who’ve helped clean up old stockrooms know long-forgotten drums don’t just disappear on their own and can create lingering hazards.
UN Number: UN 2810 (toxic liquid, organic, n.o.s.)
Proper Shipping Name: Toxic liquids, organic, n.o.s.
Packing Group: II (medium hazard)
Hazard Class: 6.1 (toxic)
Rules for road and air change country by country, and skipping steps in labeling or documenting shipments causes security, environmental, and legal headaches on arrival.
OSHA Status: Covered under hazardous chemical mandates
TSCA Status: Listed as a research or chemical intermediate
HazCom: Requires clear hazard labels, training for all handlers
Regulation exists because shortcuts cause real suffering. Over years working alongside both regulators and those they oversee, I’ve seen practical rule enforcement move the needle more than any paperwork ever could.