© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 1,2,4,5-Tetrachlorobenzene
Chemical Formula: C6H2Cl4
Synonyms: Tetrachlorobenzene, Benzene, 1,2,4,5-tetrachloro-, TCB
CAS Number: 95-94-3
Recommended Use: Chemical synthesis, intermediate, industrial manufacturing
Manufacturer: Supply chain, chemical distributor, direct industrial procurement
Emergency Contact: Local emergency agencies, Poison Control, supplier’s on-call safety division
Classification: Acute toxicity (oral, inhalation), skin irritation, environmental hazard (aquatic chronic toxicity)
Signal Word: Warning
Hazard Statements: Toxic if swallowed, harmful if inhaled, toxic to aquatic life with long lasting effects, may cause skin irritation, slight eye irritation possible
Pictograms: Skull and crossbones, exclamation mark, dead fish/tree symbol
Precautionary Statements: Avoid release to environment, wash hands thoroughly after handling, wear protective gloves, do not eat, drink, or smoke when handling
Routes of Entry: Inhalation, ingestion, dermal absorption, ocular exposure
Chemical Identity: 1,2,4,5-Tetrachlorobenzene
Concentration: 99%+ typical purity
Molecular Weight: 215.89 g/mol
Ingredient(s): 1,2,4,5-Tetrachlorobenzene (single compound)
Impurities: Trace levels of polychlorinated benzene isomers
Additives: No stabilizers or additives known in pure product
Inhalation: Remove exposed person to fresh air right away, check for breathing, give oxygen if available, seek medical attention for symptoms like coughing, wheezing, or shortness of breath
Skin Contact: Remove contaminated clothing and rinse skin under running water for at least 15 minutes, wash with mild soap, do not use solvents or thinners, seek medical advice if irritation or redness appears
Eye Contact: Flush open eyes with plain water for 15 minutes lifting upper and lower eyelids, remove contacts, get medical help especially if irritation or pain continues
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, do not induce vomiting, immediate medical attention is critical
Symptoms/Effects: Dizziness, headache, nausea, skin redness, respiratory discomfort
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, use water spray for cooling containers but not direct stream
Specific Hazards: Releases toxic gases such as phosgene, hydrogen chloride, and chlorinated compounds when burned, dangerous fumes, dense black smoke
Protective Equipment: Self-contained breathing apparatus, full protective firefighting gear
Special Procedures: Move containers away from fire if safe, avoid runoff into sewers or waterways, stay upwind, keep unauthorized persons out
Combustion Products: Chlorine, hydrogen chloride, phosgene, particulate matter
Personal Precautions: Use personal protective equipment, ventilate area, keep unprotected persons away, avoid breathing vapors or touching spilled material
Environmental Precautions: Prevent product from entering drains, waterways, or soil, notify local authorities if a significant release occurs
Methods for Cleanup: Cover spill with inert absorbent like sand, earth, or vermiculite, transfer material to a sealed, labelled container for disposal, decontaminate area thoroughly, use non-sparking tools
Spill Response: Wear compatible protective gear (gloves, goggles, respirator), limit spread, contain and recover if safe
Handling: Keep containers tightly closed, avoid inhalation or skin contact, never eat, drink or smoke while working, wash thoroughly after handling
Storage: Store in cool, dry, well-ventilated area, ambient temperature, away from incompatible substances (strong oxidizers, acids, alkalis), keep away from heat, sparks, open flames
Incompatibilities: Oxidizers, reducing agents, direct sunlight
Container Requirements: Corrosion-resistant, tightly sealed, clearly labelled, check regularly for leaks or deterioration
Exposure Limit Values: No established OSHA or ACGIH TLVs, recommend minimizing exposure as much as possible
Engineering Controls: Use adequate local exhaust ventilation, eyewash stations and safety showers near work areas, controls to prevent airborne release
Personal Protective Equipment (PPE): Impervious gloves (nitrile, neoprene), safety goggles, full-length clothing or lab coat, chemical-resistant boots, NIOSH-approved respirators if risk of vapor or dust exposure
Hygiene Measures: Always wash hands after handling, remove contaminated clothing before eating or leaving workplace, keep PPE clean and regularly inspected
Monitoring Procedures: Regular air monitoring in areas with frequent use, maintain exposure records
Appearance: White to pale yellow crystalline powder
Odor: Weak aromatic, chlorinated odor
Melting Point: 139–142°C
Boiling Point: 287–288°C
Flash Point: Not easily ignited, estimated above 110°C
Vapor Pressure: Very low at room temperature (0.02 mm Hg at 25°C)
Water Solubility: Insoluble, negligible
Density: 1.6 g/cm³ (approximate)
Partition Coefficient (log Kow): 4.3–4.7
Stability: Can sublime at room temperature, remains stable if stored properly
Chemical Stability: Stable under ordinary conditions of use and storage
Reactivity: No highly reactive properties but decomposes above 400°C with toxic byproducts
Hazardous Reactions: May react vigorously with strong oxidizers, fire, or intense heat
Hazardous Decomposition Products: Phosgene, hydrogen chloride, carbon monoxide, other chlorinated organic compounds on burning
Conditions to Avoid: Sources of ignition, strong acids/oxidizers, high heat or direct sunlight
Polymerization: Not known to occur
Acute Toxicity: Harmful if swallowed or inhaled, LD50 (oral, rat) approx 1100 mg/kg
Skin/Eye Contact: Mild irritation possible through prolonged/repeated contact
Inhalation: Symptoms include respiratory tract irritation, dizziness, possible headaches or nausea
Chronic Effects: Possible cumulative toxicity with frequent exposure, potential to affect liver and kidneys with long-term use
Carcinogenicity: Not classified by IARC, NTP or OSHA as carcinogen
Mutagenicity: No significant data, handle as potential mutagen based on chemical structure
Other Effects: May cause central nervous system depression at high dose
Ecotoxicity: Extremely toxic to aquatic organisms, LC50 (fish, 96h) 0.4–0.8 mg/L
Persistence and Degradability: Low biodegradability, persistent in environment, resists natural breakdown
Bioaccumulative Potential: High, readily accumulates in aquatic organisms, potential for biomagnification
Mobility in Soil: Low due to poor water solubility
Other Adverse Effects: Risk of long-term adverse effects in aquatic environments, contaminates sediment
Disposal Methods: Place in approved, clearly labelled hazardous waste container, dispose through licensed hazardous waste contractor, incineration recommended for large quantities
Decontamination: Clean equipment and surfaces with suitable solvent, avoid water discharge
Special Precautions: Do not flush into surface water, sanitary sewer, or natural environment
Regulations: Observe all local, state, and national requirements on hazardous chemical disposal
UN Number: 2760
Shipping Name: Tetrachlorobenzenes, solid
Transport Hazard Class: 6.1 (Toxic substance)
Packing Group: III (minor hazard)
Label Requirements: Toxic (skull and crossbones), environmental hazard
Special Precautions: Transport in original, tightly closed containers, keep separate from foodstuffs, secure against shifting or container damage, comply with ADR, IMDG, IATA-DGR regulations
US Regulations: Listed under TSCA Inventory, CERCLA Reportable Quantity 100 pounds, SARA 313 (reportable under TRI), not classified under RCRA as hazardous waste but may meet criteria depending on impurities
EU Regulations: REACH registered, subject to restrictions under the POPs Regulation as persistent organic pollutant
Canada: Listed on DSL/NDSL, subject to environmental regulations and reporting
Other Requirements: Comply with workplace exposure standards, label and handle as hazardous chemical, retains tracking requirements for environmental emissions and releases, maintain readily accessible safety documentation onsite
