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Material Safety Data Sheet: 1,2,3,6-Tetrahydrobenzaldehyde

Identification

Product Name: 1,2,3,6-Tetrahydrobenzaldehyde
Chemical Formula: C7H8O
Synonyms: Cyclohex-3-enecarbaldehyde
Recommended Use: Intermediate in organic synthesis, fragrance industries
Manufacturer: Chemical manufacturers, aromatic compound suppliers
Contact Information: Contact data for supplier safety officers or hazardous materials departments
Emergency Phone Number: National Poison Control or local emergency response hotline
CAS Number: 10443-46-4

Hazard Identification

GHS Classification: Flammable liquid, harmful if swallowed, skin and eye irritant
Signal Word: Warning
Hazard Statements: May cause mild to moderate irritation to skin, eyes, and respiratory tract; flammable vapors can form explosive mixtures with air; ingestion can cause nausea or dizziness
Pictograms: Exclamation mark, flame
Precautionary Statements: Wear protective gloves, keep away from heat and ignition sources, use only in well-ventilated areas, do not breathe mist or vapor, avoid contact with eyes and skin

Composition / Information on Ingredients

Chemical Name: 1,2,3,6-Tetrahydrobenzaldehyde
Purity: Typically >97%
Impurities: Traces of unreacted precursors, minor aromatic compounds (<1%)
Molecular Weight: 108.14 g/mol
EC Number: 600-132-4

First Aid Measures

Inhalation: Move affected person to fresh air, keep warm and at rest, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin immediately with plenty of water for at least 15 minutes, seek advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, continue rinsing, call physician
Ingestion: Rinse mouth without inducing vomiting, drink water if conscious, seek immediate medical care
Important Symptoms: Burning sensation, headache, cough, redness, stomach upset

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, alcohol-resistant foam, carbon dioxide
Unsuitable Media: Direct water jet could spread material
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, potentially irritating fumes
Protective Equipment: Standard firefighting protective clothing, self-contained breathing apparatus
Specific Hazards: Vapor is heavier than air, can travel to distant ignition sources, containers may explode from heat

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors
Protective Measures: Use gloves, goggles, protective clothing, respiratory protection if exposure risk high
Methods for Cleaning Up: Absorb spillage with inert material (sand, earth), collect in closed containers for disposal, wash spill area thoroughly, prevent runoff into drains or waterways
Environmental Precautions: Avoid release into soil or water, do not empty into drains

Handling and Storage

Precautions for Safe Handling: Use only in well-ventilated spaces, avoid inhalation, avoid skin and eye contact, prohibit smoking or open flames near product, employ explosion-proof electrical equipment
Storage Conditions: Keep tightly closed in cool, dry, and well-ventilated area away from heat, sources of ignition, strong acids or bases, oxidizing agents
Incompatible Materials: Strong acids, bases, oxidizers, reducing agents
Special Requirements: Store in original container, use secondary containment

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust ventilation, fume hoods, chemical-resistant flooring
Personal Protective Equipment: Approved chemical goggles, nitrile or neoprene gloves, flame-retardant laboratory coat
Respiratory Protection: If exposure limits are exceeded, use half or full-face respirator with organic vapor cartridge
Hygiene Measures: Wash hands thoroughly after use, avoid eating or drinking in work area, remove contaminated clothing before leaving the area
Exposure Limits: No established OSHA or ACGIH limits, minimize exposure as low as possible

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Aromatic, pungent, slightly sweet
Melting Point: -20°C
Boiling Point: 187-191°C
Flash Point: 78°C
Density: Approximately 1.0 g/cm³
Solubility: Slightly soluble in water, miscible with most organic solvents
Vapor Pressure: 0.6 mmHg at 25°C
pH: Not applicable (neutral compound)
Partition Coefficient (n-octanol/water): Estimated log Kow ~2.5

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Exposure to strong heat sources, flames, sparks, static electricity
Materials to Avoid: Oxidizing agents, acids, bases
Hazardous Decomposition: Carbon oxides, irritant organic vapors
Possibility of Hazardous Reactions: Polymerization unlikely, avoid mixing with incompatible substances

Toxicological Information

Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Effects: Skin or eye irritation, headache, nausea, dizziness upon exposure to high vapor levels
Chronic Effects: Repeated or prolonged exposure may cause dermatitis or respiratory irritation
LD50 Oral (rat): Estimated at over 1500 mg/kg
Carcinogenicity: Not classified as carcinogenic by IARC or NTP
Mutagenicity/Teratogenicity: No significant data indicating risk
Symptoms: Redness, dryness, discomfort, gastrointestinal distress

Ecological Information

Ecotoxicity: Limited data, potential toxicity to aquatic organisms in higher concentrations
Persistence and Degradability: Biodegradable under aerobic conditions
Bioaccumulative Potential: Moderate, due to lipophilic character
Mobility in Soil: Likely to adsorb to soils, moderate volatility
Other Adverse Effects: Avoid uncontrolled release, as high concentrations can affect aquatic environments

Disposal Considerations

Methods of Disposal: Incinerate at approved chemical waste facility, follow local, regional, and national regulations
Contaminated Packaging: Treat empty containers as hazardous, do not reuse, send to licensed recycler or waste disposal contractor
Precautions: Prevent spillage, avoid release to environment, never pour down drains

Transport Information

UN Number: 1993
Shipping Name: Flammable liquid, n.o.s. (contains 1,2,3,6-Tetrahydrobenzaldehyde)
Transport Hazard Class: 3
Packing Group: III
Marine Pollutant: Not classified
Special Precautions: Ensure packaging undamaged, keep away from ignition sources, secure containers during transport, emergency schedule F-E S-E

Regulatory Information

OSHA: Hazardous chemical as defined in Hazard Communication Standard
TSCA Status: Listed
REACH Status: Pre-registered where applicable for import or supply in EU
SARA Title III: Not subject to section 313 reporting
State Regulations: Check exposures under state workplace regulations
Label Requirements: Comply with hazard pictograms, signal words, and precautionary statements under GHS/CLP systems