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Product Name: 1,2,3,5-Tetrachlorobenzene
Synonyms: Tetrachlorobenzene, Tetrachlorobenzol
Chemical Formula: C6H2Cl4
CAS Number: 634-66-2
Recommended Use: Research, intermediate in organic synthesis, chemical analysis
Supplier Name: Laboratory or industrial chemical suppliers
Emergency Contact: Refer to local regulations and supplier emergency lines
Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation, Environmental hazard (aquatic chronic)
Hazard Symbols: Exclamation mark, Environment
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, toxic to aquatic life with long lasting effects
Precautionary Statements: Avoid release to environment, wear protective gloves, wash exposed skin thoroughly after use, do not eat or drink when handling
Route of Exposure: Inhalation, skin, eyes, ingestion
Target Organs: Liver, kidneys, central nervous system
Chemical Name: 1,2,3,5-Tetrachlorobenzene
CAS Registry Number: 634-66-2
Content: ≥99%
Impurities: Other chlorinated benzenes (≤1%)
Molecular Weight: 215.89 g/mol
Inhalation: Move affected person to fresh air, rest, keep warm, call for medical help if symptoms persist or worsen
Skin Contact: Remove contaminated clothing, immediately wash skin with soap and water for several minutes, seek medical evaluation if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, get medical attention if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, offer water if conscious, seek immediate medical advice
Symptoms: Nausea, irritation, drowsiness, headache, dermatitis, coughing, sore throat, abdominal pain
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray (do not use straight stream)
Fire Hazard: Flammable vapors may be released at high temperatures
Hazardous Combustion Products: Hydrogen chloride gas, phosgene, carbon oxides, other toxic fumes
Special Protective Equipment: Self-contained breathing apparatus, full protective gear, avoid inhaling smoke
Precautions: Move containers from fire area if safe, cool exposed drums with water spray
Personal Precautions: Avoid breathing dust or vapors, evacuate area, use proper personal protection
Environmental Precautions: Prevent entry to sewers, drains, soil, and waterways, inform local authorities if large spill occurs
Containment: Dike spill for recovery, use inert absorbent (sand or earth), do not touch or walk through spilled material
Cleanup Methods: Collect residue in suitable, labeled containers for disposal, ventilate area, wash spill site after material cleanup is complete
Disposal: Dispose of waste according to national and local regulations
Handling: Avoid contact with skin, eyes, avoid inhalation of dust and vapors, use only in a well-ventilated area, prevent build-up of static electricity
Hygiene Measures: Wash hands before eating, drinking, or using restroom, remove contaminated clothing and wash before reuse
Storage Conditions: Store in tightly closed, labeled containers, keep away from incompatible substances (oxidizers, acids), store in a cool, dry, ventilated area, protect from direct sunlight, segregate from food and feedstuffs
Storage Incompatibility: Avoid strong bases, oxidizing agents
Engineering Controls: Use local exhaust ventilation, preferably in fume hoods or with extraction systems to minimize airborne concentrations
Occupational Exposure Limits: No specific limits set by OSHA, ACGIH, NIOSH, but handle as hazardous
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile, neoprene), safety goggles or faceshield, long-sleeved clothing, lab coat, proper respiratory protection if ventilation is inadequate
Environmental Controls: Emission controls to prevent release into environment
Appearance: White crystalline solid
Odor: Mild aromatic odor
Melting Point: 137-140°C
Boiling Point: 258°C
Flash Point: 138°C (closed cup)
Density: 1.7 g/cm³
Solubility in Water: Insoluble
Solubility (other): Soluble in organic solvents such as ether, benzene
Vapor Pressure: 0.0012 mm Hg at 25°C
Partition Coefficient (log Kow): 4.3
pH: Not applicable
Autoignition Temperature: Not available
Evaporation Rate: Not available
Stability: Stable under recommended storage and handling conditions
Thermal Decomposition: May release toxic gases (hydrogen chloride, phosgene, carbon oxides) at high temperatures
Reactivity: Reacts with strong oxidizing agents, bases
Hazardous Polymerization: Not expected under normal conditions
Conditions to Avoid: Heat, open flames, sparks, direct sunlight, contact with incompatible substances
Acute Toxicity: Harmful if ingested or inhaled, irritates skin and mucous membranes
LD50 (Oral, rat): Approx. 2600 mg/kg
LD50 (Dermal, rabbit): Data not available
Inhalation: Risk of respiratory tract irritation, dizziness, nausea
Skin: Redness, itching, dermatitis
Eyes: Irritation, tearing
Chronic Effects: Prolonged exposure may damage liver, kidneys, possibly central nervous system
Sensitization: Not categorized as sensitizer, but repeated exposure may worsen underlying conditions
Carcinogenicity: Not listed by IARC, NTP, OSHA as known carcinogen
Mutagenicity: Not enough data to classify
Reproductive Toxicity: No conclusive studies
Aquatic Toxicity: Toxic to aquatic organisms, causes long-term adverse effects
Persistence and Degradability: Persistent in the environment, decomposes slowly
Mobility in Soil: Low mobility, tends to adsorb in soil and sediment
Bioaccumulative Potential: High potential due to log Kow value
Other Effects: Harmful to fish, algae, and invertebrates, accumulation poses risk up the food chain
Waste Treatment Methods: Dispose as hazardous waste, incineration preferred under controlled conditions
Packaging Disposal: Use certified disposal contractors, triple rinse and puncture before recycling or disposal
Disposal Precautions: Do not dispose into sewer, surface water, or soil, observe all regional, national, and local laws
Special Considerations: Label waste for content and hazard, keep waste away from incompatible chemicals
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (1,2,3,5-Tetrachlorobenzene)
Transport Hazard Class: 9
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Prevent release during transport, handle with appropriate spill kits and protective equipment
Labeling Requirements: Marine Pollutant, Miscellaneous Dangerous Substances and Articles
U.S. Regulations: Listed under TSCA, subject to SARA Title III reporting for toxic release inventory
EU Regulations: Included in REACH registration, subject to CLP Regulation (EC No 1272/2008)
Canada: DSL/NDSL listed
Other Country-Specific Regulations: Subject to chemical regulations in key industrial regions globally
Hazard Ratings (NFPA): Health 2, Flammability 1, Reactivity 0, Special Hazard: None
GHS Classification: Acute Toxicity (H302, H332), Skin and Eye Irritation (H315, H319), Hazardous to aquatic environment (H400, H410)
