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Product Name: 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-Octanesulfonic Acid
Chemical Family: Perfluoroalkyl sulfonic acid
CAS Number: 375-73-5
Synonyms: Perfluorooctane sulfonic acid, PFOS
Recommended Use: Surfactant, wetting agent, certain specialty chemical applications, laboratory reagent
Supplier: (Enter supplier information here, such as address and emergency contact hotline)
Restrictions: Industrial use only; not intended for food, drug, or household applications
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation, Reproductive toxicity, Specific target organ toxicity – repeated exposure
Signal Word: Danger
Hazard Statements: Toxic if swallowed, Toxic in contact with skin, Toxic if inhaled, Causes skin irritation, Causes serious eye irritation, May cause damage to organs through prolonged or repeated exposure, Suspected of damaging fertility or the unborn child, Very toxic to aquatic life with long lasting effects
Precautionary Statements: Wear protective gloves/protective clothing/eye protection/face protection, avoid breathing dust/vapors/mist, wash thoroughly after handling, avoid release to the environment, collect spillage, get medical advice/attention if exposed or concerned
Chemical Name: 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-Octanesulfonic Acid
CAS Number: 375-73-5
Concentration: ≥98% by weight
Impurities: Water (≤2%), possible traces of related perfluoroalkyl compounds
Inhalation: Move into fresh air immediately. Keep at rest in a position comfortable for breathing. Seek medical attention even if symptoms are not immediately present. Monitor respiration and provide oxygen if breathing becomes difficult.
Skin Contact: Remove contaminated clothing and rinse skin with plenty of water for at least 15 minutes. Wash affected area with soap and water. Do not delay obtaining medical advice.
Eye Contact: Rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing and promptly seek medical attention.
Ingestion: Rinse mouth. Do not induce vomiting. If conscious, give water to rinse mouth and drink small amounts of water. Never give anything by mouth to an unconscious person. Immediate medical attention required.
Symptoms: Symptoms may include respiratory distress, skin and eye irritation, abdominal pain, nausea, headache, and possible delayed organ effects.
Flammability: Not flammable or combustible
Suitable Extinguishing Media: Use extinguishing agents suitable for surrounding fire (water spray, alcohol-resistant foam, dry chemical, carbon dioxide). Chemical itself does not burn, but may decompose under fire conditions.
Hazardous Combustion Products: May emit toxic fumes of hydrogen fluoride, sulfur oxides, carbonyl fluoride, and other perfluorinated compounds
Firefighter Protection: Self-contained breathing apparatus, full protective clothing including chemical goggles and face shield. Keep upwind, avoid inhaling vapors or decomposition products. Cool fire-exposed containers with water spray.
Further Advice: Prevent fire-fighting runoff from entering drains or watercourses. Contaminated water may pose additional hazards.
Personal Precautions: Evacuate unnecessary personnel from area, ventilate area, avoid breathing vapors, dust, or mist, wear appropriate personal protective equipment including respiratory protection, gloves, protective clothing, and safety goggles.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Do not allow product to enter drains, surface water, or ground water. Notify authorities in case of large spills.
Containment and Cleanup: Use inert absorbent materials (sand, vermiculite) to contain spill. Collect residue and place in suitable, labeled containers for disposal. Thoroughly wash contaminated area with water and detergent. Decontaminate tools and equipment.
Waste Disposal: Dispose in compliance with all relevant local, regional, and national environmental regulations.
Handling: Handle in well-ventilated areas, avoid breathing vapors or contact with skin and eyes. Wear appropriate protective equipment. Do not ingest or allow contact with food, beverages, or smoking materials. Avoid creation of dust or aerosols.
Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place away from sources of ignition, strong acids and bases, oxidizing agents, and incompatible substances. Keep away from food, drink, animal feed. Protect against physical damage, temperature extremes, and moisture.
Storage Class: Corrosive substances, toxic solid substances
Special Requirements: Keep container labeled and securely sealed. Check regularly for leaks or deterioration.
Incompatible Materials: Avoid contact with strong reducing agents, heat, acids, bases.
Occupational Exposure Limits: No established occupational exposure limit (OEL) for this substance; follow general chemical hygiene practices and minimize exposure
Engineering Controls: Provide local exhaust ventilation or work in a chemical fume hood. Use closed process equipment or appropriate containment.
Personal Protective Equipment (PPE): Chemical-resistant gloves (such as nitrile), safety glasses or goggles, face shield, laboratory coat or chemical apron, respiratory protection if ventilation is inadequate or dust/mist is generated.
Hygiene Practices: Wash hands thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid eating, drinking, or smoking in areas where this chemical is handled.
Environmental Exposure Controls: Prevent contamination of soil, water sources, and drains.
Appearance: White to off-white solid (may appear as a crystalline powder or granules)
Odor: None, or faintly acidic
Odor Threshold: Not available
pH (solution): Strongly acidic (typically <2 in aqueous solution)
Melting Point/Freezing Point: Around 190–193°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not available
Flammability: Not flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Relative Density: Approx 1.7–2.0 (at 20°C)
Solubility: Soluble in water, alcohols, slightly soluble in organic solvents
Partition Coefficient (n-octanol/water): High (tends to partition to water phase)
Auto-Ignition Temperature: Not applicable
Decomposition Temperature: >200°C
Viscosity: Not applicable for solid
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Incompatible with strong reducing agents, alkali metals, and strong bases. Decomposes on heating to emit toxic fumes
Hazardous Reactions: May react with above-mentioned substances to generate hazardous products
Decomposition Products: Hydrogen fluoride, sulfur oxides, carbonyl fluoride, perfluorinated byproducts
Conditions to Avoid: Excess heat, direct sunlight, contamination with incompatible substances, moisture
Polymerization: Will not occur under normal process conditions
Acute Toxicity: Oral, dermal, and inhalation routes are all highly toxic with low LD50 values in animal studies
Skin/Eye Irritation: Causes severe skin irritation and serious eye damage
Sensitization: Not classified as a skin sensitizer, but repeated contact increases risk
Repeated Dose Toxicity: Evidence from animal studies shows damage to liver, thyroid, immune system
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA, but long-term exposure has raised concerns
Mutagenicity: Not mutagenic in standard tests
Reproductive Toxicity: Suspected human reproductive and developmental toxicant
Additional Effects: Persistent, bioaccumulative; can accumulate in human tissues with repeated exposure
Symptoms of Exposure: May cause headache, nausea, vomiting, fatigue, skin and mucous membrane irritation, organ dysfunction with chronic exposure
Ecotoxicity: Extremely toxic to aquatic organisms; long-lasting effects; causes fish and invertebrate mortality at low concentrations
Persistence and Degradability: Highly persistent, not readily biodegradable, remains in environment for many years
Bioaccumulation: Tends to bioaccumulate in aquatic and terrestrial organisms, including humans
Mobility in Soil: Can leach to groundwater
Other Adverse Effects: Poses serious risks to ecosystems near contaminated sites, including endocrine disruption, reproductive impairment in aquatic wildlife
Waste Generation: Avoid unnecessary waste generation by reusing if possible
Product Disposal: Incinerate in a licensed hazardous waste facility with exhaust gas scrubbing to manage emissions of hydrogen fluoride and sulfur oxides
Contaminated Packaging: Treat as hazardous material; thoroughly rinse and dispose of according to relevant regulations
Environmental Restrictions: Prevent release into environment; do not dispose via drainage or in non-controlled landfills
Regulations: Consult local, regional, and national waste management authorities for proper disposal protocols; stricter controls may apply where product is restricted
UN Number: UN 2922
Proper Shipping Name: Corrosive liquid, toxic, N.O.S. (contains perfluorooctane sulfonic acid)
Transport Hazard Class: 8 (Corrosive), 6.1 (Toxic)
Packing Group: II
Labels Required: Corrosive, Toxic
Special Precautions: Protect against spillage and leaks; use secondary containment. Ensure that emergency response information accompanies shipment.
Environmental Hazards: Classified as a marine pollutant; prevent transport release into waterways
International Inventory Status: Not listed or restricted in most international inventories (REACH, TSCA, DSL); subject to Stockholm Convention for certain applications
US Regulations: Listed on TSCA inventory with strict regulation, subject to EPA significant new use rules and reporting standards
Canadian Regulations: Subject to New Substance Notification Regulations
European Union: Substance of Very High Concern (SVHC) under REACH, restrictions apply
Japan: Controlled under Chemical Substances Control Law
Other National/Regional Controls: Many countries restrict, prohibit, or require reporting of production, import, and use
Label Requirements: Hazard pictogram, signal word, hazard and precautionary statements as per GHS
Other Information: Users are responsible for compliance with local, national, and international regulations, including workplace safety, emissions, waste, and transport rules
